Bergmanson J P, Söderberg P G, Philipson B T
Acta Ophthalmol (Copenh). 1986 Jun;64(3):312-7. doi: 10.1111/j.1755-3768.1986.tb06926.x.
A phase contrast microscopy investigation of 18 cultured rat lenses was undertaken. After an initial latent phase, the outline of the epithelial cells anteriorly became enhanced and posteriorly the lens fibers began to swell. This was followed by an anterior and posterior subcapsular accumulation of fluid, epithelial swelling and formation of posterior subcapsular vacuoles. At the end of the incubation period, no increase in the light dissemination from the lens was observed. It is concluded, that, when these changes are taken into account, the closed system cultured rat lens is an excellent and applicable model for studying the induced progressive changes in the microstructure of the living lens due to different agents.
对18个培养的大鼠晶状体进行了相差显微镜检查。在初始潜伏期后，前部上皮细胞轮廓增强，后部晶状体纤维开始肿胀。随后在前部和后部囊下出现液体积聚、上皮肿胀和后部囊下空泡形成。在孵育期结束时，未观察到晶状体的光散射增加。得出的结论是，考虑到这些变化，封闭系统培养的大鼠晶状体是研究不同因素引起的活晶状体微观结构渐进性变化的优秀且适用的模型。
