Ohlsson A, Bailey T, Takieddine F
Acta Paediatr Scand. 1986 Jul;75(4):540-4. doi: 10.1111/j.1651-2227.1986.tb10246.x.
To study the etiology of neonatal septicemia and factors associated with outcome, all charts of neonates with bacteremia and clinical sepsis admitted to a neonatal unit in Saudi Arabia, from 1 November 1980 to 31 October 1984 were reviewed. The results were compared to a previous study period in the unit (1 November 1976-31 October 1980). Septicemia was diagnosed on 50 occasions in 49 neonates. The incidence of neonatal sepsis among patients born in the hospital was 2.5/1,000 live births. Mortality from sepsis was 33% and was associated with neutropenia in 63%. The most commonly isolated bacteria were E. coli, Klebsiella and Staphylococcus aureus. Salmonella enteritidis serotypes were isolated in 4% of the cases. Group B streptococci (GBS) were isolated, for the first time, from blood of 3 neonates. Salmonella species were less frequently and GBS more often isolated than previously. GBS have now appeared as etiologic organisms in neonatal sepsis also in Saudi Arabia. Salmonella septicemia remains more common in Saudi Arabia than in the West.
为研究新生儿败血症的病因及与预后相关的因素，我们回顾了1980年11月1日至1984年10月31日期间入住沙特阿拉伯一家新生儿病房的所有患菌血症和临床败血症新生儿的病历。并将结果与该病房之前的研究时期（1976年11月1日至1980年10月31日）进行了比较。49名新生儿共50次被诊断为败血症。在该医院出生的患者中，新生儿败血症的发病率为2.5/1000活产儿。败血症的死亡率为33%，其中63%与中性粒细胞减少有关。最常分离出的细菌是大肠杆菌、克雷伯菌和金黄色葡萄球菌。4%的病例中分离出肠炎沙门氏菌血清型。首次从3名新生儿的血液中分离出B组链球菌（GBS）。与之前相比，沙门氏菌属分离得较少，而GBS分离得较多。在沙特阿拉伯，GBS现在也已成为新生儿败血症的病原生物。在沙特阿拉伯，沙门氏菌败血症仍然比西方更常见。
