Richette Pascal, Coates Laura C, Azevedo Valderilio F, Cappelleri Joseph C, Moser Jade, Queiro-Silva Ruben, Fallon Lara, Kessouri Meriem
Rheumatology Department, Lariboisière Hospital, Lariboisière, University of Paris, Paris, France.
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Rheumatol Ther. 2022 Jun;9(3):823-838. doi: 10.1007/s40744-022-00435-y. Epub 2022 Mar 17.
To compare perceptions of disease control and treatment satisfaction between patients with psoriatic arthritis (PsA) in North America and Europe, and between participating countries within each region.
Data were collected from patients with self-reported PsA diagnoses using an online survey. Results from questions on perceptions of overall health, disease severity, PsA symptoms, PsA impacts, and treatment satisfaction/preferences were reported using descriptive statistics and Chi-square tests.
A total of 456 patients from North America (Canada, n = 155; US, n = 301) and 417 patients from Europe (France, n = 123; Spain, n = 135; UK, n = 159) were included in this analysis. Patients in North America were more likely to rate their overall health as excellent/good compared with those in Europe (49 vs. 14%), but also rate their disease as severe (27 vs. 15%). Despite treatment, patients in North America and Europe still experienced musculoskeletal (92 vs. 91%) and skin/nail (62 vs. 58%) symptoms. Similar proportions of patients in North America vs. Europe experienced a social impact (81 vs. 85%); more patients in Europe vs. North America experienced PsA-related work impacts (83 vs. 74%). Satisfaction with PsA medication was more common in North America (89%) vs. Europe (79%), and more common in Spain (91%) vs. the UK (82%) or France (66%). Across all regions and countries, ≥ 75% of patients agreed that symptoms were controlled. However, ≥ 66% wished they had more medication choices, and ≥ 84% wanted to change something about their medication.
Although perception of overall health and disease severity varied, many patients from both regions still experienced symptoms despite receiving medications for PsA, wished they had greater choice of medications, and/or would like to change an aspect of their medications. While these survey findings are subject to selection bias, they do indicate there is scope to improve the treatment of PsA.
比较北美和欧洲银屑病关节炎(PsA)患者之间以及各地区参与国家内部对疾病控制和治疗满意度的看法。
通过在线调查收集自我报告患有PsA诊断的患者的数据。使用描述性统计和卡方检验报告有关总体健康、疾病严重程度、PsA症状、PsA影响以及治疗满意度/偏好的问题结果。
本分析纳入了来自北美的456名患者(加拿大,n = 155;美国,n = 301)和来自欧洲的417名患者(法国,n = 123;西班牙,n = 135;英国,n = 159)。与欧洲患者相比,北美患者更有可能将他们的总体健康评为优秀/良好(49%对14%),但也将他们的疾病评为严重(27%对15%)。尽管接受了治疗,北美和欧洲的患者仍有肌肉骨骼症状(92%对91%)和皮肤/指甲症状(62%对58%)。北美和欧洲经历社会影响的患者比例相似(81%对85%);欧洲经历PsA相关工作影响的患者比北美更多(83%对74%)。对PsA药物的满意度在北美(89%)比欧洲(79%)更常见,在西班牙(91%)比英国(82%)或法国(66%)更常见。在所有地区和国家,≥75%的患者同意症状得到了控制。然而,≥66%的患者希望他们有更多的药物选择,≥84%的患者希望改变他们的药物治疗方案。
尽管对总体健康和疾病严重程度的看法有所不同,但两个地区的许多患者尽管接受了PsA药物治疗仍有症状,希望有更多的药物选择,和/或希望改变他们药物治疗的某个方面。虽然这些调查结果存在选择偏倚,但它们确实表明改善PsA治疗存在空间。