Putz Ellie J, Bayles Darrell O, Alt David P, Nally Jarlath E
Infectious Bacterial Disease Research Unit, USDA Agriculture Research Service, National Animal Disease Center, Ames, IA, USA.
J Genomics. 2022 Feb 14;10:45-48. doi: 10.7150/jgen.69822. eCollection 2022.
Pathogenic species of cause leptospirosis, a global zoonotic disease affecting humans and all major livestock species. Cattle act as a reservoir host for . serovar Hardjo which colonize the kidneys and reproductive tract from which they are excreted and transmitted to other cattle via urine, semen or uterine discharges. Bovine leptospirosis results in reproductive failure, abortion, stillbirth and loss of milk production, and is an occupational risk for those working with infected animals. A recent study determined that 7.2% of cattle from an abattoir in the central United States were actively shedding pathogenic . Here, we report and compare the complete genome sequence of four recent isolates of . serovar Hardjo designated strain TC112, TC147, TC129, and TC273.
某些病原体可引发钩端螺旋体病,这是一种影响人类和所有主要家畜物种的全球性人畜共患病。牛是这些病原体的储存宿主。其中,哈焦血清型(Hardjo serovar)可定殖于牛的肾脏和生殖道,并通过尿液、精液或子宫分泌物排出,进而传播给其他牛。牛钩端螺旋体病会导致繁殖失败、流产、死产以及产奶量下降,对于接触感染动物的工作人员而言,还存在职业风险。最近一项研究表明,美国中部一家屠宰场中7.2%的牛正在主动排出致病性病原体。在此,我们报告并比较了哈焦血清型(Hardjo serovar)的四个近期分离株(分别命名为TC112、TC147、TC129和TC273菌株)的完整基因组序列。