Anichkov N M, Mamaev N N, Mamaeva S E, Skripnik S V
Arkh Patol. 1986;48(6):87-91.
The paper deals with some methods studying chromosome set in tumour cells. The latest data on tumour chromosome aberrations are reported. The latter are subdivided by the authors into non-specific and specific, characteristic only of certain variants of tumour differentiation, and are of diagnostic significance. The authors put forward further tasks of combined oncomorphologic and cytogenetic studies of specific chromosome aberrations as a valuable marker for the diagnosis of malignancy.
本文论述了研究肿瘤细胞染色体组的一些方法。报告了有关肿瘤染色体畸变的最新数据。作者将后者分为非特异性和特异性的,特异性畸变仅为肿瘤分化的某些变体所特有,具有诊断意义。作者提出了进一步的任务,即对特定染色体畸变进行肿瘤形态学和细胞遗传学联合研究,作为诊断恶性肿瘤的一个有价值的标志物。