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慢性暴露于空气污染对心电图参数的影响。

The impact of chronic exposure to air pollution on electrocardiographic parameters.

机构信息

Military Institute of Medicine, Warsaw, Poland (Department of Cardiology and Internal Diseases).

Institute of Cardiology, Warsaw, Poland (Department of Coronary Artery Disease and Cardiac Rehabilitation).

出版信息

Int J Occup Med Environ Health. 2022 Jun 8;35(3):353-360. doi: 10.13075/ijomeh.1896.01682. Epub 2022 Mar 15.

DOI:10.13075/ijomeh.1896.01682
PMID:35302115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10464795/
Abstract

OBJECTIVES

Chronic exposure to air pollution caused by particulate matter (PM) with aerodynamic diameters of <10 μm (PM) and <2.5 μm (PM), dependent on "low emissions" resulting from the combustion of solid fuels in households, significantly increases the risk of cardiovascular events. The aim of the study was to assess the impact of chronic exposure to air pollution in the place of residence on the occurrence of coronary artery disease, hypertension and the presence of electrocardiographic abnormalities in 24-hour Holter ECG recording.

MATERIAL AND METHODS

After considering the exclusion criteria, 100 consecutive patients of the cardiology outpatient clinic were enrolled in the study, including 50 patients living for ≥10 years in Warsaw districts with the lowest average concentrations of PM (group I) and 50 living in the districts with the highest recorded exposure (group II). All patients underwent clinical and physical examination, 12-lead ECG, 2D cardiac echo, and Holter ECG. To avoid the impact of acute exposure, the study was carried out in May - the month with statistically the lowest recorded PM concentrations.

RESULTS

In the group of patients exposed to higher concentrations of PM in the place of residence, coronary artery disease and arterial hypertension were significantly more frequent, while in the Holter ECG examination, ventricular arrhythmias, conduction disturbances and ST-segment and T-wave changes were independently associated with exposure to air pollution.

CONCLUSIONS

Chronic exposure to air pollution in the place of residence contributes to the occurrence of chronic coronary syndrome and hypertension. Chronic exposure to air pollution seems to be a significant factor increasing the incidence of ventricular arrhythmia, conduction disturbances and ST-segment depression episodes in Holter monitoring. Int J Occup Med Environ Health. 2022;35(3):353-60.

摘要

目的

慢性暴露于空气中的颗粒物(PM),其空气动力学直径<10μm(PM)和<2.5μm(PM),取决于家庭燃烧固体燃料产生的“低排放”,会显著增加心血管事件的风险。本研究旨在评估居住环境中慢性空气污染暴露对冠状动脉疾病、高血压的发生以及 24 小时动态心电图记录中心电图异常的影响。

材料和方法

在考虑排除标准后,本研究纳入了 100 名连续的心脏病门诊患者,包括 50 名在华沙区居住≥10 年的患者,这些区的 PM 平均浓度最低(I 组),以及 50 名居住在记录暴露浓度最高区的患者(II 组)。所有患者均接受了临床和体格检查、12 导联心电图、二维心脏超声和动态心电图检查。为避免急性暴露的影响,该研究于 5 月进行,这是 PM 记录浓度统计上最低的月份。

结果

在居住环境中暴露于较高浓度 PM 的患者组中,冠状动脉疾病和动脉高血压更为常见,而在动态心电图检查中,室性心律失常、传导障碍以及 ST 段和 T 波改变与空气污染暴露独立相关。

结论

居住环境中的慢性空气污染暴露会导致慢性冠状动脉综合征和高血压的发生。慢性暴露于空气污染似乎是增加动态心电图监测中心律失常、传导障碍和 ST 段压低发作的重要因素。国际职业医学与环境卫生杂志。2022;35(3):353-60.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c8d/10464795/e9bd0b3dbc9b/ijomeh-35-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c8d/10464795/e9bd0b3dbc9b/ijomeh-35-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c8d/10464795/e9bd0b3dbc9b/ijomeh-35-353-g001.jpg

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Lancet Planet Health. 2017 May;1(2):e58-e64. doi: 10.1016/S2542-5196(17)30020-7. Epub 2017 May 5.
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