Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Department of Psychology, Ludwig-Maximilians-University, Munich, Germany.
Sci Adv. 2022 Mar 18;8(11):eabl6037. doi: 10.1126/sciadv.abl6037.
Humans predominantly explore their environment by moving their eyes. To optimally communicate and process visual information, neural activity needs to be coordinated with the execution of eye movements. We investigated the coordination between visual exploration and interareal neural communication by analyzing local field potentials and single neuron activity in patients with epilepsy. We demonstrated that during the free viewing of images, neural communication between the human amygdala and hippocampus is coordinated with the execution of eye movements. The strength and direction of neural communication and hippocampal saccade-related phase alignment were strongest for fixations that landed on human faces. Our results argue that the state of the human medial temporal lobe network is selectively coordinated with motor behavior. Interareal neural communication was facilitated for social stimuli as indexed by the category of the attended information.
人类主要通过移动眼睛来探索环境。为了最佳地交流和处理视觉信息，神经活动需要与眼动的执行相协调。我们通过分析癫痫患者的局部场电位和单个神经元活动，研究了视觉探索和脑区间神经通讯之间的协调。我们证明，在自由观看图像时，人类杏仁核和海马体之间的神经通讯与眼球运动的执行相协调。神经通讯的强度和方向以及与海马体扫视相关的相位对准最强的是落在人脸的注视点上。我们的结果表明，人类内侧颞叶网络的状态与运动行为选择性地协调。以被关注信息的类别为指标，促进了脑区间的神经通讯。
