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评估高强度聚焦超声联合吸引刮除术治疗外源性剖宫产瘢痕妊娠。

Evaluation of the treatment of high intensity focused ultrasound combined with suction curettage for exogenous cesarean scar pregnancy.

机构信息

Department of Gynecology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, Zhejiang, China.

Department of Ultrasound, The Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, Zhejiang, China.

出版信息

Arch Gynecol Obstet. 2022 Sep;306(3):769-777. doi: 10.1007/s00404-022-06487-3. Epub 2022 Mar 18.

Abstract

PURPOSE

To evaluate the effectiveness of high-intensity focused ultrasound (HIFU) combined with suction curettage in the treatment of exogenous cesarean scar pregnancy (CSP).

METHODS

A retrospective single-center observational study was conducted. A total of 41 patients diagnosed with exogenous CSP were enrolled in this study. All patients received HIFU combined with suction curettage.

RESULTS

Twenty-nine patients were administered one session of HIFU ablation. In addition, the other 12 patients received 2 HIFU sessions. Suction curettage was performed in all patients after HIFU, and no patient was converted to laparoscopy or hysterectomy. The mean blood loss during suction curettage was 99 ml. Three patients received two sessions of suction curettage. The success rate of our study was 92.68%. The mean time for serum β-HCG normalization was 23.18 ± 3.13 days. The average menstruation recovery time was 29.38 ± 3.34 days. Based on the blood loss during suction curettage, 41 patients were divided into a bleeding group and a control group. The size of the gestational sac in the bleeding group (3.80 ± 0.87 cm) was larger than that in the control group (3.39 ± 0.77 cm) (P < 0.05). The thickness of the myometrium between the bladder and gestational sac in the bleeding group (2.37 ± 0.89 mm) was less than that in the control group (2.75 ± 0.75 mm) (P < 0.05).

CONCLUSION

The results suggested that HIFU combined with suction curettage could be considered an effective treatment for exogenous CSP of < 9 weeks. The size of the gestational sac and the thickness of the myometrium between the bladder and gestational sac might be high-risk factors for blood loss during this treatment.

摘要

目的

评估高强度聚焦超声(HIFU)联合吸引刮宫术治疗外源性剖宫产瘢痕妊娠(CSP)的效果。

方法

本研究为回顾性单中心观察性研究。共纳入 41 例外源性 CSP 患者,均接受 HIFU 联合吸引刮宫术治疗。

结果

29 例行 1 次 HIFU 消融,12 例行 2 次 HIFU 治疗。HIFU 后所有患者均行刮宫术,无一例中转腹腔镜或开腹手术。刮宫术平均出血量 99ml,3 例因出血行 2 次刮宫术。本研究成功率为 92.68%。血清β-HCG 正常化时间的平均时间为 23.18±3.13 天,平均月经恢复时间为 29.38±3.34 天。根据刮宫术出血量,将 41 例患者分为出血组和对照组。出血组妊娠囊大小(3.80±0.87cm)大于对照组(3.39±0.77cm)(P<0.05),出血组膀胱与妊娠囊之间的子宫肌层厚度(2.37±0.89mm)小于对照组(2.75±0.75mm)(P<0.05)。

结论

HIFU 联合吸引刮宫术治疗<9 周外源性 CSP 效果确切,妊娠囊大小和膀胱与妊娠囊之间的子宫肌层厚度可能是影响术中出血量的高危因素。

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