Obstetrics and Gynecology, Health Sciences University Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Turkey.
J Obstet Gynaecol Res. 2022 Jun;48(6):1348-1354. doi: 10.1111/jog.15229. Epub 2022 Mar 18.
This study aimed to evaluate the difference in fetal thymus diameter, which we measured ultrasonographically, between the healthy pregnant group and the pregnant group with gestational diabetes.
Fetal thymus and thymus/thorax ratio parameters were assessed in this case-control study. Patients were examined in two groups. They included 49 diabetics (study group) women and 71 nondiabetic (control group). We performed a binary logistic regression analysis to determine the predictive value of ultrasonographic measurements. We completed the receiver curve characteristic analysis to evaluate the cut-off thymus diameter.
The median age of pregnant women was 27. Thymus diameter and thymus-thorax ratio were smaller in fetuses of diabetic mothers than in the nondiabetic group (p <0.05). Thymus diameter was found to be more predictive of gestational diabetes prediction (p: 0.019). There was no correlation between fasting blood glucose and thymus diameter.
Decreased fetal thymus anterior-posterior diameter seems to be associated with diabetic pregnancy.
本研究旨在评估正常妊娠组与妊娠期糖尿病组孕妇胎儿胸腺直径的差异，我们通过超声进行了测量。
在这项病例对照研究中评估了胎儿胸腺和胸腺/胸廓比参数。将患者分为两组：49 名糖尿病（研究组）妇女和 71 名非糖尿病（对照组）。我们进行了二元逻辑回归分析以确定超声测量的预测价值。我们完成了接收曲线特征分析以评估胸腺直径的截止值。
孕妇的中位年龄为 27 岁。糖尿病母亲的胎儿胸腺直径和胸腺/胸廓比小于非糖尿病组（p<0.05）。胸腺直径对预测妊娠期糖尿病更具预测性（p：0.019）。空腹血糖与胸腺直径之间无相关性。
胎儿前-后胸腺直径的减小似乎与糖尿病妊娠有关。
