Ghalandarpoor-Attar Seyedeh Noushin, Borna Sedigheh, Ghalandarpoor-Attar Seyedeh Mojgan, Hantoushzadeh Sedigheh, Khezerdoost Soghra, Ghotbizadeh Fahimeh
Department of Obstetrics and Gynecology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.
J Matern Fetal Neonatal Med. 2020 Apr;33(7):1157-1161. doi: 10.1080/14767058.2018.1517309. Epub 2018 Sep 25.
To investigate the correlation between fetal thymus size and diabetes in pregnancy. Fetal thymus size was assessed in 160 pregnant women with gestational age of 19-39 weeks. They included 80 diabetic (investigation group) and 80 nondiabetic (control group) women. Fetal thymus size was measured by thymic-thoracic ratio. We did this with dividing the thymus' anteroposterior diameter by anteroposterior of mediastinum. Thymic-thoracic ratio was significantly smaller in fetuses of diabetic mothers compared to the nondiabetic group ( = .001). It remained significant after subgrouping diabetic mothers into overt diabetes, insulin-dependent gestational diabetes, and noninsulin-dependent gestational diabetes. Although thymus size was smaller in fetuses of diabetic pregnant women compared to nondiabetic pregnant women, it seems that thymic-thoracic ratio can be a predictor of diabetes and its other related adverse effects during pregnancy.
为研究胎儿胸腺大小与妊娠期糖尿病之间的相关性。对160名孕周为19 - 39周的孕妇进行胎儿胸腺大小评估。其中包括80名糖尿病孕妇（研究组）和80名非糖尿病孕妇（对照组）。通过胸腺 - 胸廓比值测量胎儿胸腺大小。我们通过将胸腺前后径除以前纵隔前后径来进行此项测量。与非糖尿病组相比，糖尿病母亲所生胎儿的胸腺 - 胸廓比值显著更小（P = 0.001）。将糖尿病母亲亚组分为显性糖尿病、胰岛素依赖型妊娠期糖尿病和非胰岛素依赖型妊娠期糖尿病后，该差异仍具有显著性。尽管与非糖尿病孕妇相比，糖尿病孕妇所生胎儿的胸腺大小较小，但胸腺 - 胸廓比值似乎可作为妊娠期糖尿病及其其他相关不良影响的一个预测指标。
