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皮肤软组织肿瘤的免疫组织化学及分子学新进展

Immunohistochemical and molecular updates in cutaneous soft tissue neoplasms.

作者信息

Chukwudebe Olisaemeka, Brown Ryanne A

机构信息

Office of Planning, Research, and Institutional Effectiveness, Cañada College, Redwood City, CA 94061, United States of America.

Pathology and Laboratory Services, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94305, United States of America; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, United States of America; Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, United States of America.

出版信息

Semin Diagn Pathol. 2022 Jul;39(4):257-264. doi: 10.1053/j.semdp.2022.02.004. Epub 2022 Feb 19.

Abstract

Accurate classification of soft tissue neoplasms of the skin and subcutis can be challenging given the sometimes significant histomorphologic and immunohistochemical overlap between the entities that comprise this ever-expanding category of tumors. With the benefit of continually emerging adjuncts to histologic diagnosis, pathologists have a number of tools at their disposal for navigating this group of neoplasms. This article aims to review recent immunohistochemical and molecular updates in the diagnosis of cutaneous soft tissue neoplasms.

摘要

鉴于构成这一不断扩大的肿瘤类别的实体之间有时存在显著的组织形态学和免疫组化重叠,准确分类皮肤和皮下软组织肿瘤可能具有挑战性。得益于不断出现的组织学诊断辅助手段,病理学家有多种工具可用于处理这类肿瘤。本文旨在综述皮肤软组织肿瘤诊断中免疫组化和分子方面的最新进展。

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