Mechanisms Underlying Dysregulation of miR-132 in Alzheimer's Disease.
作者信息
Song Qiaoyun, Dou Juan, Mao Zixu, Wen Zhexing, Li Wenming
机构信息
Department of Pharmacology and Chemical biology, Emory University School of Medicine, USA.
Department of Reproductive Genetics, Hebei General Hospital, PR China.
出版信息
Biomed J Sci Tech Res. 2019;22(5):17018-17020. doi: 10.26717/bjstr.2019.22.003824. Epub 2019 Nov 15.
Abstract
摘要
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本文引用的文献
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Cureus. 2019 Sep 5;11(9):e5573. doi: 10.7759/cureus.5573.
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Environmental enrichment prevents Aβ oligomer-induced synaptic dysfunction through mirna-132 and hdac3 signaling pathways.环境富集通过 mirna-132 和 hdac3 信号通路预防 Aβ 寡聚体诱导的突触功能障碍。
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MicroRNA-132 promotes neurons cell apoptosis and activates Tau phosphorylation by targeting GTDC-1 in Alzheimer's disease.MicroRNA-132 通过靶向 Alzheimer 病中的 GTDC-1 促进神经元细胞凋亡并激活 Tau 磷酸化。
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microRNA dysregulation in neurodegenerative diseases: A systematic review.microRNA 失调与神经退行性疾病：系统综述。
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miR-132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity.miR-132 抑制核糖体蛋白的转录，以促进保护性 Th1 免疫。
EMBO Rep. 2019 Apr;20(4). doi: 10.15252/embr.201846620. Epub 2019 Mar 4.
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MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways.miRNA-132 通过多种信号通路为 tau 病提供神经保护。
Acta Neuropathol. 2018 Oct;136(4):537-555. doi: 10.1007/s00401-018-1880-5. Epub 2018 Jul 7.
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MicroRNA-132 modifies angiogenesis in patients with ischemic cerebrovascular disease by suppressing the NF‑κB and VEGF pathway.微小 RNA-132 通过抑制 NF-κB 和 VEGF 通路调节缺血性脑血管病患者的血管生成。
Mol Med Rep. 2018 Feb;17(2):2724-2730. doi: 10.3892/mmr.2017.8138. Epub 2017 Nov 22.
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Advances in Roles of miR-132 in the Nervous System.miR-132在神经系统中的作用研究进展
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FASEB J. 2017 Feb;31(2):424-433. doi: 10.1096/fj.201601308.
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