Azin Farahnaz, Khazali Homayoun
Department of Animal Science and Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.
Int J Reprod Biomed. 2022 Feb 18;20(1):13-20. doi: 10.18502/ijrm.v20i1.10404. eCollection 2022 Jan.
Polycystic ovary syndrome (PCOS) is a complex heterogeneous disease with various symptoms, which can affect females of reproductive age. Endocrine and metabolic abnormalities such as infertility, being overweight or obese, type 2 diabetes, hyperandrogenism and increased luteinizing hormone (LH) are common in women with PCOS.
This review aimed to assess the efficacy of non-chemical and herbal substances for PCOS recovery.
The keywords "non-chemical treatment", "herbal treatment", "polycystic ovary syndrome" and "PCOS" were used to search for articles in the electronic databases PubMed/MEDLINE, Web of Science, Scopus, and Reaxys, published from January 2009 to December 2019.
34 relevant studies were found and were briefly described in this review. The most effective herbal treatments in animal models of PCOS were used to restore abnormality in serum sex steroid profile, LH: follicle stimulating hormone ratio, steroidogenic enzymes, cardiovascular parameters, lipid profile, and glucose and estrous cycles. In PCOS patients, positive effects on PCOS due to reductions in testosterone, estrogen, LH, LH: follicle stimulating hormone ratio, and insulin levels were observed.
The results of this reviewrevealed the variability and efficacy of phytotherapy and non-chemical treatments associated with PCOS disease. These findings may help future studies on the etiology and treatment of this syndrome.
多囊卵巢综合征（PCOS）是一种具有多种症状的复杂异质性疾病，可影响育龄女性。内分泌和代谢异常，如不孕、超重或肥胖、2型糖尿病、高雄激素血症以及黄体生成素（LH）升高，在PCOS女性中很常见。
本综述旨在评估非化学物质和草药对PCOS恢复的疗效。
使用关键词“非化学治疗”“草药治疗”“多囊卵巢综合征”和“PCOS”在电子数据库PubMed/MEDLINE、科学网、Scopus和Reaxys中检索2009年1月至2019年12月发表的文章。
共找到34项相关研究，并在本综述中进行了简要描述。在PCOS动物模型中，最有效的草药治疗用于恢复血清性类固醇谱、LH：卵泡刺激素比值、类固醇生成酶、心血管参数、血脂谱以及血糖和发情周期的异常。在PCOS患者中，观察到由于睾酮、雌激素、LH、LH：卵泡刺激素比值和胰岛素水平降低而对PCOS产生的积极影响。
本综述结果揭示了与PCOS疾病相关的植物疗法和非化学治疗的变异性和疗效。这些发现可能有助于未来对该综合征病因和治疗的研究。
