Piispa Ilona, Karjalainen Karoliina, Karttunen Niina
University of Eastern Finland, Kuopio, Finland.
Finnish Institution for Health and Welfare, Helsinki, Finland.
Nordisk Alkohol Nark. 2022 Feb;39(1):64-75. doi: 10.1177/14550725211018082. Epub 2021 Jun 10.
Nonmedical use of prescription drugs (NMUPD) is a major public health concern. The aim of the study was to compare intoxication-oriented users to those who utilised prescription drugs nonmedically for other purposes. The characteristics of the study groups, prescription drugs used, motivations for their use and sources of prescription drugs were also examined.
Data were derived from the population-based Drug Survey 2014 which was conducted in Finland. The respondents were divided into intoxication-oriented users ( = 118) and other nonmedical users ( = 74) according to the motivation behind their NMUPD. The reference population ( = 3277) did not report any NMUPD. Pearson's chi square test was used to compare the distributions. A multinomial logistic regression model was used to estimate the association of sociodemographic background and intoxicant use with NMUPD.
Low education level and illegal drug use were associated with intoxication-oriented and other nonmedical use of prescription drugs. Intoxication-oriented use was associated also with younger age and current smoking. Sedatives were the most commonly used prescription drugs among intoxication-oriented users, and opioids among other nonmedical users. Experimentation and facilitating social interactions as a motivation for use were emphasised among intoxication-oriented users. Friends and relatives were the most common sources of prescription drugs for nonmedical use, especially among intoxication-oriented users.
The characteristics, motivations and sources of nonmedically used prescription drugs differed in intoxication-oriented and other nonmedical users. These findings may help to identify those at risk for NMUPD. More attention should be paid to the motivations of NMUPD when new prevention and intervention methods are developed.
处方药的非医疗使用是一个主要的公共卫生问题。本研究的目的是比较以中毒为目的的使用者与出于其他目的非医疗使用处方药的人。还对研究组的特征、使用的处方药、使用动机以及处方药来源进行了调查。
数据来自于在芬兰进行的基于人群的2014年药物调查。根据非医疗使用处方药背后的动机,将受访者分为以中毒为目的的使用者(n = 118)和其他非医疗使用者(n = 74)。参考人群(n = 3277)未报告任何非医疗使用处方药的情况。使用Pearson卡方检验比较分布情况。使用多项逻辑回归模型估计社会人口背景和毒品使用与非医疗使用处方药之间的关联。
低教育水平和非法药物使用与以中毒为目的和其他非医疗使用处方药有关。以中毒为目的的使用还与较年轻的年龄和当前吸烟有关。镇静剂是在以中毒为目的的使用者中最常用的处方药,而阿片类药物在其他非医疗使用者中最常用。在以中毒为目的的使用者中,强调将试验和促进社交互动作为使用动机。朋友和亲戚是处方药非医疗使用的最常见来源,尤其是在以中毒为目的的使用者中。
以中毒为目的的使用者和其他非医疗使用者在非医疗使用处方药的特征、动机和来源方面存在差异。这些发现可能有助于识别非医疗使用处方药的风险人群。在开发新的预防和干预方法时,应更多地关注非医疗使用处方药的动机。