AlYami Ali H, Alosaimi Majed N, Alshehri Mohammed S, Alghamdi Abdulhamid T, SaemAldahar Majd A, Alsafrani Turki A, Dabroom Albaraa A, Kattan Ibrahim A, Sindi Fares M, Azaya Azzam M, AlMaeen Bandar N
Department of Surgery, Ministry of National Guard Health Affairs, Jeddah, SAU.
Department of Surgery, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Cureus. 2022 Feb 13;14(2):e22171. doi: 10.7759/cureus.22171. eCollection 2022 Feb.
Background Hip fracture is a major medical and surgical topic and is a significant cause of morbidity and mortality. Older women, especially those with osteoporosis, are at an increased risk for hip fractures. Multiple studies have shown the effect of osteoporosis on the refracture rate among the elderly population. Therefore, selecting a targeted population for screening and treating osteoporosis has an essential role in decreasing the hip fracture rate. This study aimed to determine the association between osteoporosis treatment and refracture rate among patients with hip fractures at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Methods Collected data included patient demographics (men: ≥55 years old; women: ≥50 years old), the used osteoporosis investigation method, osteoporosis treatment history, presence of comorbidities, and refracture as a primary outcome. The refracture rate among patients with hip fracture was calculated and used to determine the association between hip refracture and osteoporosis. Results Our study included a total of 292 patients who presented to our hospital due to hip fractures. The patients were divided into two groups, the osteoporotic and non-osteoporotic groups. These groups were then compared. There was no statistical significance between osteoporosis and hip refracture (p = 0.721), and there was no association between the treatment of osteoporosis and hip refracture (p = 0.493). Statistical difference was found between patients who had undergone dual-energy X-ray absorptiometry scan and were not treated for osteoporosis (p = 0.00). Lastly, the mortality of the refracture group was 10%, while it was 11% in the no-refracture group (p = 1.00). Conclusion Morbidity and mortality rates are higher among patients with hip fractures. Our study showed that there was no association between hip refracture rate and osteoporosis whether the patient is treated for osteoporosis or not. We recommend a systematic review that can include more studies in this field to acquire more definitive results regarding this topic.
髋部骨折是一个重要的医学和外科课题，是发病和死亡的重要原因。老年女性，尤其是患有骨质疏松症的女性，髋部骨折风险增加。多项研究表明骨质疏松症对老年人群再骨折率的影响。因此，选择有针对性的人群进行骨质疏松症筛查和治疗对于降低髋部骨折率具有重要作用。本研究旨在确定沙特阿拉伯吉达阿卜杜勒阿齐兹国王医疗城髋部骨折患者骨质疏松症治疗与再骨折率之间的关联。
收集的数据包括患者人口统计学信息（男性：≥55岁；女性：≥50岁）、所采用的骨质疏松症调查方法、骨质疏松症治疗史、合并症情况以及作为主要结局的再骨折情况。计算髋部骨折患者的再骨折率，并用于确定髋部再骨折与骨质疏松症之间的关联。
我们的研究共纳入292例因髋部骨折前来我院就诊的患者。患者分为两组，骨质疏松组和非骨质疏松组。然后对这两组进行比较。骨质疏松症与髋部再骨折之间无统计学意义（p = 0.721），骨质疏松症治疗与髋部再骨折之间也无关联（p = 0.493）。在接受双能X线吸收测定扫描且未接受骨质疏松症治疗的患者之间发现有统计学差异（p = 0.00）。最后，再骨折组的死亡率为10%，而未再骨折组为11%（p = 1.00）。
髋部骨折患者的发病率和死亡率较高。我们的研究表明，无论患者是否接受骨质疏松症治疗，髋部再骨折率与骨质疏松症之间均无关联。我们建议进行系统评价，纳入该领域更多研究，以获得关于该主题更明确的结果。
