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术前焦虑水平对心脏手术后疼痛的影响。

Influence of Preoperative Anxiety Level on Postoperative Pain After Cardiac Surgery.

作者信息

Kashif Muhammad, Hamid Mohammad, Raza Amir

机构信息

Department of Anesthesiology, Aga Khan University Hospital, Karachi, PAK.

出版信息

Cureus. 2022 Feb 13;14(2):e22170. doi: 10.7759/cureus.22170. eCollection 2022 Feb.

Abstract

Background Preoperative anxiety is generally neglected in the evaluation of cardiac surgery patients due to various reasons including insufficient literature and lack of simple assessment tools. In addition to this, the association between anxiety and postoperative complications including pain has been scarcely studied. The present study was designed to assess preoperative anxiety levels in all patients coming for cardiac surgery and then evaluate the effect of different levels of anxiety on postoperative pain scores. Methods This prospective cohort study was conducted in a single university hospital from March 2018 to December 2019. One hundred consecutive cardiac surgery patients between the ages of 18-65 years were enrolled in this study. The level of preoperative anxiety (assessed by State Anxiety Inventory) and its effect on postoperative pain and morphine consumption was assessed. Results The average age of the patients was 58.24±10.03 years of which 68% were male and 32% were female. Preoperative mild anxiety was observed in 64% of patients and moderate to severe anxiety in 36% of patients. Post-operative mean pain score was significantly high in the moderate to severe anxiety group as compared to the mild anxiety group [Mean pain difference =1.64 (95%CI: 1.38-1.89) p=0.0005], [Mean pain difference =0.51 (95%CI: 0.29-0.73) p=0.0005] at 12 hours and 24 hours respectively. Intraoperative and postoperative morphine consumption was significantly high in patients with moderate to severe anxiety. Conclusions Patients with moderate to severe anxiety before cardiac surgery experienced higher pain scores at a post-operative period which is significantly different from the mild anxiety group. Intraoperative and postoperative analgesic requirements were also significantly increased.

摘要

背景

由于包括文献不足和缺乏简单评估工具等各种原因,术前焦虑在心脏手术患者评估中普遍被忽视。除此之外,焦虑与包括疼痛在内的术后并发症之间的关联鲜有研究。本研究旨在评估所有接受心脏手术患者的术前焦虑水平,然后评估不同焦虑水平对术后疼痛评分的影响。

方法

本前瞻性队列研究于2018年3月至2019年12月在一家大学医院进行。连续纳入100例年龄在18 - 65岁之间的心脏手术患者。评估术前焦虑水平(采用状态焦虑量表评估)及其对术后疼痛和吗啡用量的影响。

结果

患者的平均年龄为58.24±10.03岁,其中68%为男性,32%为女性。64%的患者术前存在轻度焦虑,36%的患者存在中度至重度焦虑。与轻度焦虑组相比,中度至重度焦虑组术后平均疼痛评分在12小时和24小时时显著更高[平均疼痛差异=1.64(95%CI:1.38 - 1.89),p = 0.0005],[平均疼痛差异=0.51(95%CI:0.29 - 0.73),p = 0.0005]。中度至重度焦虑患者术中及术后吗啡用量显著更高。

结论

心脏手术前中度至重度焦虑的患者在术后经历更高的疼痛评分,这与轻度焦虑组有显著差异。术中及术后镇痛需求也显著增加。

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