Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Fašmon Durjava Mojca, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Dierick Noël, Tarrés-Call Jordi, Galobart Jaume, Anguita Montserrat, Ortuño Jordi
EFSA J. 2022 Mar 11;20(3):e07165. doi: 10.2903/j.efsa.2022.7165. eCollection 2022 Mar.
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of manganous lysinate sulfate as nutritional feed additive for all animal species. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP Panel) was assigned to this mandate. Based on the results of a tolerance study, the FEEDAP Panel concluded that manganous lysinate sulfate is safe for chickens for fattening when used up to the current maximum authorised levels of total manganese in feed; this conclusion was extrapolated to all animal species and categories at the respective maximum manganese levels in complete feed authorised in the EU. The FEEDAP Panel concluded that the use of manganous lysinate sulfate in animal nutrition at the maximum manganese levels authorised for the animal species poses no concern to the safety of consumers and the environment. The Panel also concluded that manganous lysinate sulfate poses a risk to users by inhalation, is irritant to eyes and skin and should be considered a dermal sensitiser. Based on the results of a bioequivalence study, the FEEDAP Panel concluded that manganous lysinate sulfate is considered efficacious for chickens for fattening as a nutritional additive. This conclusion was extrapolated to all animal species and categories.
应欧盟委员会的要求，欧洲食品安全局（EFSA）被要求就硫酸锰赖氨酸作为所有动物物种营养饲料添加剂的安全性和有效性提供科学意见。动物饲料添加剂和产品或物质专家小组（FEEDAP小组）被赋予了这项任务。基于一项耐受性研究的结果，FEEDAP小组得出结论，硫酸锰赖氨酸在用于育肥鸡时，若使用量达到饲料中总锰的当前最高授权水平，则是安全的；这一结论被外推至欧盟批准的全价饲料中各自最高锰水平下的所有动物物种和类别。FEEDAP小组得出结论，在动物营养中按照动物物种授权的最高锰水平使用硫酸锰赖氨酸，对消费者安全和环境不构成担忧。该小组还得出结论，硫酸锰赖氨酸通过吸入对使用者构成风险，对眼睛和皮肤有刺激性，应被视为皮肤致敏剂。基于一项生物等效性研究的结果，FEEDAP小组得出结论，硫酸锰赖氨酸作为营养添加剂对育肥鸡被认为是有效的。这一结论被外推至所有动物物种和类别。
