Nüssler Emil, Granåsen Gabriel, Bixo Marie, Löfgren Mats
Department of Clinical Sciences, Obstetrics and Gynaecology, Umeå University, 901 85, Umeå, Sweden.
Int Urogynecol J. 2022 Jul;33(7):1863-1873. doi: 10.1007/s00192-022-05156-y. Epub 2022 Mar 21.
Pelvic organ prolapse (POP) is common, and women have an estimated 12-19% lifetime risk for needing POP surgery. Aims were to measure re-operation rates up to 10 years after POP surgery and patient-reported outcomes (PROMs) 5 years after a first-time operation for POP.
This is a cohort study using the Swedish National Quality Register for Gynaecological Surgery (GynOp). We retrieved information from 32,086 POP-operated women up to 10 years later. After validation, a web-based PROM questionnaire was sent to 4380 women who 5 years previously had standard POP surgery. Main outcome measures were reoperations due to a relapse of prolapse and PROMs 5 years after the primary operation.
Among women operated for all types of POP, 11% had re-operations 5 years later and an additional 4% 10 years later, with similar frequencies for various compartments/types of surgery. PROMs yielded a 75% response rate after 5 years. Cure rate was 68% for anterior, 70% for posterior, and 74% for combined anterior-posterior native repairs. Patient satisfaction exceeded 70%, and symptom reduction was still significant after 5 years (p < 0.0001).
Following primary prolapse surgery, re-operation rates are low, even after 10 years. A web-based survey for follow-up of PROMs after POP surgery is feasible and yields a high response rate after 5 years. The subjective cure rate after primary POP operations is high, with reduced symptoms and satisfied patients regardless of compartment. Standard prolapse surgery with native tissue repair produces satisfactory long-term results.
盆腔器官脱垂(POP)很常见,据估计女性一生中需要进行POP手术的风险为12%-19%。本研究旨在测量POP手术后长达10年的再次手术率以及首次POP手术后5年患者报告的结局(PROMs)。
这是一项使用瑞典国家妇科手术质量登记册(GynOp)的队列研究。我们在长达10年后从32086名接受POP手术的女性中获取信息。经过验证后,向4380名5年前接受标准POP手术的女性发送了基于网络的PROM问卷。主要结局指标是因脱垂复发导致的再次手术以及初次手术后5年的PROMs。
在接受各种类型POP手术的女性中,5年后11%的人进行了再次手术,10年后另有4%的人进行了再次手术,不同腔室/手术类型的频率相似。5年后PROMs的回复率为75%。前壁修复的治愈率为68%,后壁修复为70%,前后壁联合原位修复为74%。患者满意度超过70%,5年后症状减轻仍然显著(p<0.0001)。
初次脱垂手术后,即使在10年后再次手术率也很低。基于网络的POP手术后PROMs随访调查是可行的,5年后回复率很高。初次POP手术后主观治愈率很高,无论腔室如何,症状均减轻且患者满意。采用原位组织修复的标准脱垂手术可产生令人满意的长期效果。