Ernst Lisa, Schilling Georgia
Medizinische Fakultät: Asklepios Campus Hamburg, Semmelweis Universität Budapest, Lohmühlenstr. 5, Haus P, 20099, Hamburg, Deutschland.
Internistisch-onkologische Rehabilitation, Asklepios Nordseeklinik Westerland/Sylt, Westerland/Sylt, Deutschland.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022 Apr;65(4):420-430. doi: 10.1007/s00103-022-03504-3. Epub 2022 Mar 21.
The number of long-term survivors of malignant diseases is steadily increasing, which is due to the further development and optimization of multimodal therapy strategies and the mechanisms of new substance classes. These can now be combined with classical treatment methods or used sequentially. At the same time the number of patients who suffer from physical and psychosocial long-term consequences of cancer therapies or have to live with chronic side effects under the long-term therapies increases. Every therapy, whether radiation, chemotherapy, targeted therapy, or operation, has undesirable long-term side effects that contribute to the decrease of one's quality of life. These affect all parts of the body. As a result, patients can be heavily burdened. In oncology and in other disciplines involved in aftercare, these consequences must therefore be increasingly addressed and clarified and treatment strategies further developed. Unfortunately, there is still a considerable need for research in this area; moreover, there is a lack of clinical studies examining the evidence of a wide variety of holistic therapy methods.
恶性疾病长期存活者的数量在稳步增加,这归因于多模式治疗策略的进一步发展与优化以及新物质类别的作用机制。现在这些可以与传统治疗方法联合使用或序贯应用。与此同时,遭受癌症治疗的身体和心理社会长期后果或在长期治疗下不得不忍受慢性副作用的患者数量增加。每种治疗方法,无论是放疗、化疗、靶向治疗还是手术,都有不良的长期副作用,这些副作用会导致生活质量下降。这些副作用会影响身体的各个部位。因此,患者可能负担沉重。在肿瘤学以及参与后续护理的其他学科中,必须越来越多地关注和阐明这些后果,并进一步制定治疗策略。不幸的是,该领域仍有相当大的研究需求;此外,缺乏对多种整体治疗方法的证据进行检验的临床研究。