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[钌106/铑106治疗脉络膜恶性黑色素瘤的10年经验——264例受照射肿瘤的报告]

[10 years' experience with ruthenium 106/rhodium 106 treatment of malignant melanoma of the choroid--report on 264 irradiated tumors].

作者信息

Guthoff R, von Domarus D, Steinhorst U, Hallermann D

出版信息

Klin Monbl Augenheilkd. 1986 Jun;188(6):576-83. doi: 10.1055/s-2008-1050719.

DOI:10.1055/s-2008-1050719
PMID:3531691
Abstract

In 75% of the patients with malignant melanoma of the choroid useful vision can be retained by beta-radiation with ruthenium-106/rhodium. Tumors with a prominence of more than 6 mm should be treated only for very special reasons. There is a statistically proven correlation between the initial tumor volume and the occurrence of residual tissue volume. Histopathological investigations have shown that residuals of the tumor do not permit any conclusions concerning the dignity or vitality of tumor cells. The risk to life is not increased by the conservative procedure, and it may even be reduced.

摘要

在75%的脉络膜恶性黑色素瘤患者中,使用钌-106/铑进行β射线照射可保留有用视力。突出超过6毫米的肿瘤仅在非常特殊的情况下才应进行治疗。初始肿瘤体积与残留组织体积的发生之间存在统计学上已证实的相关性。组织病理学研究表明,肿瘤残留无法就肿瘤细胞的特性或活力得出任何结论。保守治疗方法不会增加生命风险,甚至可能降低风险。

相似文献

1
[10 years' experience with ruthenium 106/rhodium 106 treatment of malignant melanoma of the choroid--report on 264 irradiated tumors].[钌106/铑106治疗脉络膜恶性黑色素瘤的10年经验——264例受照射肿瘤的报告]
Klin Monbl Augenheilkd. 1986 Jun;188(6):576-83. doi: 10.1055/s-2008-1050719.
2
[Echocardiography findings before and following beta-irradiation (106Ru/106Rh) of choroid melanoma].
Klin Monbl Augenheilkd. 1987 Jan;190(1):17-20. doi: 10.1055/s-2008-1050320.
3
Experiences in the treatment of malignant melanoma of the choroid with 106Ru-106Rh beta-ray applicators.
Trans Ophthalmol Soc U K (1962). 1973;93(0):119-32.
4
[Radiation retinopathy following treatment of choroid melanomas with 106Ru/106Rh applicators].[使用106Ru/106Rh敷贴器治疗脉络膜黑色素瘤后的放射性视网膜病变]
Fortschr Ophthalmol. 1983;80(5):418-21.
5
[A procedure for the determination of dose performance of radioactive eye applicators (106-Ru/106-Rh) and their significance for indications and treatment in malignant choroid melanomas].[一种用于测定放射性眼部敷贴器(106-钌/106-铑)剂量性能的方法及其对恶性脉络膜黑色素瘤适应症和治疗的意义]
Klin Monbl Augenheilkd. 1985 Nov;187(5):451-4. doi: 10.1055/s-2008-1054371.
6
Techniques and results of 106Ru/106Rh radiation of choroidal tumours.脉络膜肿瘤的106钌/106铑放射治疗技术与结果
Trans Ophthalmol Soc U K (1962). 1983;103 ( Pt 1):72-7.
7
[Optimization of irradiation time in the treatment of malignant melanoma of the choroid with beta applicators (106Ru/106Rh)].[使用β敷贴器(106Ru/106Rh)治疗脉络膜恶性黑色素瘤时照射时间的优化]
Klin Monbl Augenheilkd. 1986 Aug;189(2):133-40. doi: 10.1055/s-2008-1050770.
8
Treatment of choroidal melanomas with 106Ru/106Rh beta-ray applicators.用106Ru/106Rhβ射线敷贴器治疗脉络膜黑色素瘤。
Trans Ophthalmol Soc U K (1962). 1977 Sep;97(3):428-9.
9
[The regression behavior of choroid melanoma following radiotherapy--a new prognostic parameter?].[放射治疗后脉络膜黑色素瘤的回归行为——一个新的预后参数?]
Klin Monbl Augenheilkd. 1990 Jan;196(1):6-10. doi: 10.1055/s-2008-1046119.
10
[Radiotherapy of malignant melanoma of the choroid using the ruthenium-106-applicator].[使用钌-106敷贴器治疗脉络膜恶性黑色素瘤]
Ber Zusammenkunft Dtsch Ophthalmol Ges. 1978(75):644-5.

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Br J Ophthalmol. 2005 Oct;89(10):1306-10. doi: 10.1136/bjo.2005.068460.
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[Dose-volume histogram regression analysis of uveal melanomas after single fraction gamma knife radiosurgery].[单次分割伽玛刀放射外科治疗后葡萄膜黑色素瘤的剂量体积直方图回归分析]
Ophthalmologe. 2004 Nov;101(11):1111-9. doi: 10.1007/s00347-003-0984-y.
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Calcification-like echographic patterns in uveal melanomas treated with brachytherapy.
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Br J Ophthalmol. 1993 Dec;77(12):827. doi: 10.1136/bjo.77.12.827.
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Histopathology studies in human malignant melanomas of the choroid after unsuccessful treatment with 106Ru/106Rh ophthalmic applicators.在用106Ru/106Rh眼科敷贴器治疗失败后的脉络膜恶性黑色素瘤的组织病理学研究。
Graefes Arch Clin Exp Ophthalmol. 1991;229(5):480-6. doi: 10.1007/BF00166314.
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Uveal melanoma: therapeutic consequences of doubling times and irradiation results; a review.
Int Ophthalmol. 1992 Mar;16(2):91-9. doi: 10.1007/BF00918938.