Mikhaylov Alexey Y, Yumashev Alexei V, Kolpak Eugeny
Financial Research Institute of the Ministry of Finance of the Russian Federation, Moscow, Russia.
Department of Prosthetic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Arch Med Sci. 2020 Nov 29;18(2):328-335. doi: 10.5114/aoms.2020.101359. eCollection 2022.
The aim of this study was to perform a comparative and economic analysis of the degree of development of anxiety-depressive disorder in patients with different types of extrasystolic arrhythmia using different assessment scales.
The study was conducted in 2018-2019 at the premises of clinic No. 4, involving 450 patients (Moscow, Russia). Patients were divided into three groups: with coronary heart disease (CHD) (147 patients), with myocardiodystrophy (MCD) (113) and with cardiopsychoneurosis (CPN) (190). Everyone underwent round-the-clock electrocardiography (ECG) and echocardiography. If symptoms of depressive disorder are detected in a timely manner, the risk of adverse cardiovascular diseases may be reduced.
Depression and anxiety indicators on all three scales differed significantly ( ≤ 0.05) in patients with supraventricular extrasystole (more than 40 points on the Zung scale, 14 points on the Montgomery-Asberg depression scale, more than 38 points on Zung and 3 points on Covi anxiety scales). For patients with ventricular extrasystole, a significant difference was established between groups 1 and 2 only in terms of the level of depression on the Zung scale. Factors of psychogenic origin determine the development of cardiac rhythm disturbances.
The study showed that for supraventricular extrasystoles, these factors determine the overall health of the patient. The differences between the three groups are significant on all scales of depression and anxiety ( ≤ 0.05). The most susceptible to depression and anxiety are patients with extrasystolic arrhythmias diagnosed with CHD, as well as MCD.
本研究旨在使用不同的评估量表,对不同类型早搏性心律失常患者的焦虑抑郁障碍发展程度进行比较和经济分析。
该研究于2018 - 2019年在第4诊所进行,涉及450名患者(俄罗斯莫斯科)。患者分为三组:冠心病(CHD)患者(147例)、心肌营养不良(MCD)患者(113例)和心脏神经官能症(CPN)患者(190例)。所有人均接受了24小时心电图(ECG)和超声心动图检查。如果能及时发现抑郁障碍症状,可能会降低不良心血管疾病的风险。
室上性早搏患者在所有三个量表上的抑郁和焦虑指标均有显著差异(≤0.05)(zung量表超过40分,蒙哥马利 - 阿斯伯格抑郁量表14分,zung量表超过38分,科维焦虑量表3分)。对于室性早搏患者,仅在zung量表的抑郁水平方面,第1组和第2组之间存在显著差异。心理源性因素决定了心律失常的发展。
研究表明,对于室上性早搏,这些因素决定了患者的整体健康状况。在所有抑郁和焦虑量表上,三组之间的差异均具有显著性(≤0.05)。最易患抑郁和焦虑的是被诊断患有冠心病以及心肌营养不良的早搏性心律失常患者。