Moulder Zachary, Kosela Monika, Zafar M Ahtsham, Jha Abhinav, Gopal Karthik, Pandey Anmol
University College London Medical School, London, UK.
Salford Royal NHS Foundation Trust, Salford Royal Hospital, Stott Lane, Salford, UK.
Oxf Med Case Reports. 2022 Mar 16;2022(3):omac028. doi: 10.1093/omcr/omac028. eCollection 2022 Mar.
A 36-year-old diabetic woman presented to hospital with a seizure that started with shaking of the right hand which sequentially progressed to the entire right side of the body with associated loss of consciousness. Capillary Blood Glucose was 29 mmol/L. HbA1c was 133 mmol/L. Non-contrast computerised tomography (CT) scan of the brain was normal suggesting that the cause of her seizure was hyperglycaemia. However, Magnetic Resonance Imaging (MRI) of the brain showed infarcts in the left paracentral lobule and caudate nucleus. It also identified loss of signal flow void in the intracranial segment of the left internal carotid artery (ICA) raising the suspicion for thrombosis secondary to dissection. This was later confirmed on CT angiogram. This case demonstrates how the initial CT Head was non-diagnostic. We stress the importance of taking a careful seizure history and subsequently obtaining an MRI scan to fully exclude structural pathology.
一名36岁的糖尿病女性因癫痫发作入院。发作始于右手颤抖,随后逐渐发展至右侧身体,并伴有意识丧失。毛细血管血糖为29 mmol/L。糖化血红蛋白为133 mmol/L。脑部非增强计算机断层扫描(CT)正常,提示其癫痫发作的原因是高血糖。然而,脑部磁共振成像(MRI)显示左侧中央旁小叶和尾状核梗死。MRI还发现左侧颈内动脉(ICA)颅内段信号流空消失,怀疑继发于夹层的血栓形成。这一点后来在CT血管造影中得到证实。该病例表明最初的头颅CT检查未能明确诊断。我们强调仔细询问癫痫发作病史并随后进行MRI扫描以完全排除结构性病变的重要性。