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纳米脂质体伊立替康作为三线化疗药物维持治疗胰腺癌腹膜转移患者的长期生存

Long-Term Survival of a Patient With Peritoneal Carcinomatosis From Pancreatic Cancer Maintained by Nanoliposomal Irinotecan as Third-Line Chemotherapy.

作者信息

Nagata Keiji, Kajiwara Masatoshi, Fujikawa Takahisa

机构信息

Surgery, Kokura Memorial Hospital, Kitakyushu, JPN.

Gastroenterological Surgery, Fukuoka University Hospital, Fukuoka, JPN.

出版信息

Cureus. 2022 Feb 18;14(2):e22355. doi: 10.7759/cureus.22355. eCollection 2022 Feb.

Abstract

Pancreatic cancer is still one of the most fatal neoplastic diseases, and the recurrence occurs in more than 80% of the patients even though radical resection is performed. We experienced a long-term survival case of a patient with peritoneal carcinomatosis from pancreatic cancer maintained by nanoliposomal irinotecan (nal-IRI) in combination with fluorouracil and folinic acid (FF) as third-line chemotherapy. Nal-IRI + FF combination chemotherapy is one of the promising options for the management of intractable recurrent pancreatic cancer.

摘要

胰腺癌仍然是最致命的肿瘤疾病之一,即使进行了根治性切除,仍有超过80%的患者会复发。我们经历了一例胰腺癌腹膜转移患者的长期生存病例,该患者接受纳米脂质体伊立替康(nal-IRI)联合氟尿嘧啶和亚叶酸(FF)作为三线化疗。Nal-IRI + FF联合化疗是治疗难治性复发性胰腺癌的有前景的选择之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/918b/8934406/adc8fe8aa508/cureus-0014-00000022355-i01.jpg

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