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结核性心包炎——一种隐匿且具有挑战性的疾病:病例报告

Tuberculous pericarditis-a silent and challenging disease: A case report.

作者信息

Lucero Oscar David, Bustos Marlon Mauricio, Ariza Rodríguez Darwin Jhoan, Perez Juan Camilo

机构信息

Department of Internal Medicine, Hospital Universitario San Ignacio, Bogotá 110231, Colombia.

Internal Medicine Resident, Pontificia Universidad Javeriana, Bogotá 110231, Colombia.

出版信息

World J Clin Cases. 2022 Feb 26;10(6):1869-1875. doi: 10.12998/wjcc.v10.i6.1869.

Abstract

BACKGROUND

Tuberculous pericarditis (TP) remains a challenge for endemic countries. In developing countries, one to two percent of patients with pulmonary tuberculosis develops TP.

CASE SUMMARY

A 49-year-old woman presented with dyspnea, chest pain and dry cough. On physical examination, veiled heart sounds were found. The electrocardiogram showed low-voltage complexes and the transthoracic echocardiography revealed a large and free-looking pericardial effusion. The patient was taken for an open pericardiotomy. The pericardial fluid revealed high levels of adenosine deaminase and Ziehl-Neelsen stain showed acid-fast bacilli. Polymerase chain reaction study for in pericardial fluid was positive. The patient received tetra conjugate management with adequate clinical response after the first week of treatment and resolution of fever and chest pain.

CONCLUSION

In cases of TP, obtaining pericardial fluid and/or pericardial biopsy is the most efficient strategy to confirm the diagnosis. Early diagnosis of this entity will allow physicians to initiate timely treatment, avoid complications and improve the patient's clinical outcome, so we consider the description of this case pertinent and its review in the literature.

摘要

背景

结核性心包炎(TP)对结核病流行国家来说仍是一项挑战。在发展中国家,1%至2%的肺结核患者会发展为TP。

病例摘要

一名49岁女性因呼吸困难、胸痛和干咳就诊。体格检查发现心音模糊。心电图显示低电压复合波,经胸超声心动图显示有大量且外观游离的心包积液。该患者接受了心包切开术。心包液显示腺苷脱氨酶水平升高,萋尼氏染色显示抗酸杆菌。心包液聚合酶链反应研究呈阳性。患者接受四联综合治疗,治疗第一周后临床反应良好,发热和胸痛症状缓解。

结论

对于TP病例,获取心包液和/或心包活检是确诊的最有效策略。对该疾病的早期诊断将使医生能够及时开始治疗,避免并发症并改善患者的临床结局,因此我们认为对该病例的描述及其在文献中的回顾具有相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c279/8891785/043a0c247357/WJCC-10-1869-g001.jpg

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