Department of Medicine, The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Strategic Technologies Program of the National Plan for Sciences and Technology and Innovation in the Kingdom of Saudi, Arabia (08-MED511-02), Riyadh, Saudi Arabia.
Sleep Breath. 2023 Mar;27(1):57-66. doi: 10.1007/s11325-022-02602-5. Epub 2022 Mar 22.
This article focuses on recent evidence linking rapid eye movement (REM) obstructive sleep apnea (OSA) (REM-OSA) to neurocognitive dysfunction and mood changes; the proposed mechanisms for increased risk of neurocognitive dysfunction in REM-OSA, and future research prospects.
PubMed and Google Scholar records were examined for articles utilizing pre-defined keywords. In this work, we mainly included studies published after 2017; nevertheless, critical studies published prior to 2017 were considered.
REM-OSA is an under-recognized stage-related sleep-disordered breathing in which obstructive respiratory events happen chiefly in stage REM. The disorder is commonly seen amongst younger patients and females and has recently been linked to cardiometabolic complications. Although less symptomatic than non-REM-OSA and non-stage-specific OSA, current findings indicate that REM-OSA may have neurocognitive repercussions and mood changes and could be linked to insomnia, increased dreams, and nightmares.
Currently available evidence indicates that REM-OSA may present with insomnia and nightmares and could affect cognitive function and mood.
本文重点介绍了 REM 睡眠呼吸暂停（REM-OSA）与神经认知功能障碍和情绪变化之间的关联的最新证据；提出了 REM-OSA 神经认知功能障碍风险增加的潜在机制，以及未来的研究前景。
检索了利用预定义关键词的 PubMed 和 Google Scholar 记录。在这项工作中，我们主要纳入了 2017 年后发表的研究；然而，也考虑了 2017 年前发表的重要研究。
REM-OSA 是一种未被充分认识的与年龄相关的睡眠呼吸紊乱，其中阻塞性呼吸事件主要发生在 REM 期。该疾病在年轻患者和女性中更为常见，且最近与心脏代谢并发症有关。尽管 REM-OSA 比非 REM-OSA 和非特定阶段的 OSA 的症状较少，但现有研究结果表明，REM-OSA 可能会对认知功能和情绪产生影响，并与失眠、梦境增加和噩梦有关。
目前的证据表明，REM-OSA 可能会出现失眠和噩梦，并可能影响认知功能和情绪。
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