Emeruwa A C
Mycopathologia. 1986 Jul;95(1):29-35. doi: 10.1007/BF00436319.
An intracellular beta-hemolysin capable of lysing human, sheep and cow erythrocytes but not cells from some other animals was isolated from the cell walls of the three developmental cell-forms of Nocardia asteroides and characterised. The spherical cell-forms contained the highest amounts of the hemolysin (100 h.u./mg protein) and the least LD50 for mice suggesting that this may be the cell-form most pathogenic to susceptible animals. The hemolysin has the properties of a protein, was pH stable and sensitive to both catabolite repression and temperature. The activity of the hemolysin was enhanced by Ca++ and Na+ ions. The hemolysin was immunogenic in rabbits.
从星形诺卡氏菌三种发育细胞形态的细胞壁中分离出一种细胞内β-溶血素，它能够溶解人、绵羊和牛的红细胞，但不能溶解其他一些动物的细胞，并对其进行了表征。球形细胞形态所含的溶血素量最高（100个溶血单位/毫克蛋白质），对小鼠的半数致死剂量最低，这表明这可能是对易感动物致病性最强的细胞形态。该溶血素具有蛋白质的特性，对pH稳定，对分解代谢阻遏和温度敏感。Ca++和Na+离子可增强溶血素的活性。该溶血素在兔体内具有免疫原性。
