美国加利福尼亚州免疫功能低下儿童的疫苗相关麻疹脑炎。

Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA.

出版信息

Emerg Infect Dis. 2022 Apr;28(4):906-908. doi: 10.3201/eid2804.212357.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8962891/

Abstract

We report a fatal case of vaccine-associated measles encephalitis in an immunocompromised child in California, USA. The infection was confirmed by whole-genome RNA sequencing of measles virus from brain tissue. We observed biased matrix-gene hypermutation consistent with persistent measles virus central nervous system infection.

摘要

我们报告了美国加利福尼亚州一名免疫功能低下儿童的疫苗相关麻疹脑炎致死病例。该感染通过脑组织中麻疹病毒的全基因组 RNA 测序得到证实。我们观察到偏倚的基质基因高突变，与持续性麻疹病毒中枢神经系统感染一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7ea/8962891/81b79d14350f/21-2357-F.jpg

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美国加利福尼亚州免疫功能低下儿童的疫苗相关麻疹脑炎。

Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA.

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美国加利福尼亚州免疫功能低下儿童的疫苗相关麻疹脑炎。

Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA.

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