Matthesen Astrid Thaarup, Thaarup Jesper, Hagstrøm Søren, Matthesen Kristine Thaarup, Thorsteinsson Kristina
Børneafdelingen, Aalborg Universitetshospital.
Ugeskr Laeger. 2022 Mar 21;184(12).
Tubulointerstitial nephritis and uveitis (TINU) syndrome in children is an uncommon, underreported condition. Onset of renal and ocular symptoms is often not simultaneous with nephritis which may precede uveitis by several months. A variable treatment response and a propensity for relapse characterize the syndrome. This is a case report of a previously healthy 14-year-old boy with TINU syndrome, emphasizing the need for long-term interdisciplinary treatment and monitoring. Also, the importance of repetitive screening of patients with uveitis for renal disease and ophthalmological evaluation of children with nephritis is emphasized.
儿童肾小管间质性肾炎和葡萄膜炎(TINU)综合征是一种罕见且报道不足的病症。肾脏和眼部症状的发作通常不同时出现,肾炎可能比葡萄膜炎早几个月出现。该综合征的特点是治疗反应多变且有复发倾向。本文报告一例先前健康的14岁男孩患TINU综合征的病例,强调了长期跨学科治疗和监测的必要性。此外,还强调了对葡萄膜炎患者反复进行肾脏疾病筛查以及对肾炎患儿进行眼科评估的重要性。