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[经典型和非洲型卡波西肉瘤中的人类白细胞抗原分型]

[HLA typing in classical and African Kaposi's disease].

作者信息

Lemarchand-Venencie F, Lepace V, Belaich S, Civatte J, Rabian C, Chidiac A, Colombani J, Degos L

出版信息

Pathol Biol (Paris). 1986 Jun;34(6):761-4.

PMID:3531992
Abstract

HLA A, B, C, typing have been done in 39 patients with clinically and histologically documented classical Kaposi's sarcoma. Thirty three were also typed for HLA DR antigens. Twenty seven were males, 12 were females and three ethnic groups were represented: european caucasoids 41%, north african caucasoids 38.5% and negroids 20.5%. The only statistically significant abnormality is an increase of HLA DR5 frequency (60.6 vs 26. p less than 0.001 et RR = 4.2). Such an increase has been evidenced also in AIDS patients, with or without Kaposi's sarcoma and then is not discriminant between all this different types of the disease.

摘要

对39例临床和组织学确诊为经典型卡波西肉瘤的患者进行了HLA A、B、C分型。其中33例还进行了HLA DR抗原分型。患者中男性27例,女性12例,涵盖三个种族:欧洲白种人占41%,北非白种人占38.5%,黑种人占20.5%。唯一具有统计学显著意义的异常是HLA DR5频率增加(60.6对26,p小于0.001,相对危险度=4.2)。在患有或未患有卡波西肉瘤的艾滋病患者中也证实了这种增加,因此它并不能区分所有这些不同类型的疾病。

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