[艾滋病高危人群中慢性腺病患者的人类白细胞抗原分型]
[HLA typing in patients with chronic adenopathies in a population at risk for AIDS].
作者信息
Raffoux C, David V, Couderc L J, Rabian C, Clauvel J P, Seligmann M, Colombani J
出版信息
Pathol Biol (Paris). 1986 Jun;34(6):758-60.
HLA-A B and DR typing were performed in 77 patients with AIDS related complex (ARC)--69 lymphadenopathy associated syndrome and 8 thrombocytopenic purpura LAV/HTLV III related--and 21 symptom free homosexual males. A significant increase in the frequency of HLA DR5 antigen was observed in patients with ARC mainly in purpura thrombocytopenic patients. We suggest that increase of HLA DR5 antigen support the view that DR5 antigen could be one of the factors necessary at the spreading out clinical symptoms.
对77例艾滋病相关综合征（ARC）患者——69例淋巴结病相关综合征患者以及8例血小板减少性紫癜（与LAV/HTLV III相关）患者——和21名无症状同性恋男性进行了HLA - A、B及DR分型。在ARC患者中，主要是血小板减少性紫癜患者，观察到HLA DR5抗原频率显著增加。我们认为，HLA DR5抗原频率增加支持了这样一种观点，即DR5抗原可能是临床症状出现所必需的因素之一。
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