Rowley A H, Shulman S T
Department of Pediatrics, Northwestern University Medical School, Children's Memorial Hospital, Chicago, Illinois, USA.
Pediatr Clin North Am. 1999 Apr;46(2):313-29. doi: 10.1016/s0031-3955(05)70120-6.
Kawasaki syndrome is a fascinating worldwide illness of young children. This acute self-limited vasculitis has become the most common cause of acquired heart disease in children in the United States and Japan. KS causes significant coronary artery disease that may lead to myocardial infarction and sudden death. Clinical and epidemiologic features of KS support an infectious cause, but the etiology remains unknown. Clearly, additional research on the cause of KS and its pathogenesis is needed urgently to allow for improved diagnosis; more specific therapy; and, ultimately, prevention of the disorder.
川崎病是一种在全球范围内令人着迷的幼儿疾病。这种急性自限性血管炎已成为美国和日本儿童后天性心脏病的最常见病因。川崎病会导致严重的冠状动脉疾病，可能引发心肌梗死和猝死。川崎病的临床和流行病学特征支持其由感染引起，但病因仍不明。显然，迫切需要对川崎病的病因及其发病机制进行更多研究，以便改善诊断、采用更具针对性的治疗方法，并最终预防这种疾病。
