酵母调节基因STE7的核苷酸序列预测出一种与蛋白激酶同源的蛋白质。
Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases.
作者信息
Teague M A, Chaleff D T, Errede B
出版信息
Proc Natl Acad Sci U S A. 1986 Oct;83(19):7371-5. doi: 10.1073/pnas.83.19.7371.
Abstract
The nucleotide sequence of the STE7 gene from Saccharomyces cerevisiae has been determined. It is one of several regulatory genes implicated in the control of cell-type-specific gene expression in yeast. The predicted amino acid sequence shows homology to several members of the protein kinase family. These results suggest protein phosphorylation may play a key role in regulation leading to cell-type specialization in yeast.
摘要
已测定了酿酒酵母STE7基因的核苷酸序列。它是与酵母细胞类型特异性基因表达调控相关的几个调控基因之一。预测的氨基酸序列与蛋白激酶家族的几个成员具有同源性。这些结果表明，蛋白质磷酸化可能在酵母细胞类型特化的调控中起关键作用。
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