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一名患有糖尿病酮症酸中毒的孕妇的COVID-19死亡病例。

A Case of COVID-19 Mortality in a Pregnant Woman with Diabetes Ketoacidosis.

作者信息

Aminimoghaddam Soheila, Nasiri Setareh, Abrari Aida, Yazdizadeh Maryam, Rashidi Romina

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Department of Obstetrics and Gynecology, Faculty of Medicine, Gilan University of Medical Sciences, Gilan, Iran.

出版信息

Med J Islam Repub Iran. 2021 Oct 21;35:139. doi: 10.47176/mjiri.35.139. eCollection 2021.

Abstract

SARS-CoV-2 is a newly identified virus that causes COVID 19, spreading very fast in the world. Uncontrolled diabetes in pregnancy can increase the risk of pregnancy outcomes. Pregnant women are at high risk of developing a viral infection, like SARS-COV and on the other hand, diabetes ketoacidosis (DKA) which is coupled with COVID-19, can increase maternal mortality. The patient was a 27-years-old female G3P1L1Ab1 with a history of a previous cesarean section. On 26 March 2020, a fetal ultrasound revealed intra-uterine fetal death (IUFD) and also diagnosis of DKA and COVID-19 in the patient that she was expired eventually due to the uncontrolled DKA. In this case report, a pregnant woman with a diagnosis of IUFD, DKA and COVID-19 simultaneously is described. To the best of the authors of this paper's knowledge, no previous work has been reported for the comorbidity of diabetes and COVID-19 in pregnancy, but it seems that the coincidence of the above-mentioned diseases can delay the recovery period and also can increases maternal and fetal mortality. When DKA and COVID-19 appear in the patient simultaneously, we cannot control DKA by the routine protocol treatments of DKA which were used formerly.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是一种新发现的病毒,可导致新型冠状病毒肺炎(COVID-19),在全球传播速度极快。妊娠期间未控制的糖尿病会增加不良妊娠结局的风险。孕妇感染病毒的风险很高,如感染SARS-CoV,另一方面,与COVID-19相关的糖尿病酮症酸中毒(DKA)会增加孕产妇死亡率。该患者为一名27岁的女性,孕3产1,有1次活产史,1次流产史,既往有剖宫产史。2020年3月26日,胎儿超声检查显示宫内胎儿死亡(IUFD),同时诊断该患者患有DKA和COVID-19,她最终因未控制的DKA而死亡。在本病例报告中,描述了一名同时诊断为IUFD、DKA和COVID-19的孕妇。据本文作者所知,此前尚无关于妊娠合并糖尿病和COVID-19的报道,但上述疾病的同时存在似乎会延长恢复期,还会增加孕产妇和胎儿死亡率。当患者同时出现DKA和COVID-19时,我们无法通过以前使用的DKA常规治疗方案来控制DKA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d050/8840864/d442937b48a2/mjiri-35-139-g001.jpg

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