Ghalichi Leila, Naserbakht Morteza, Eftekhar Ardebili Mehrdad, Janani Leila, Pournik Omid, Tavakoli Fatemeh, Haghdoost Ali Akbar, Sharifi Hamid
Mental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Science, Tehran, Iran.
Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Science, Tehran, Iran.
Med J Islam Repub Iran. 2021 Sep 23;35:123. doi: 10.47176/mjiri.35.123. eCollection 2021.
The need for informed policymaking highlights the importance of data on human immunodeficiency virus (HIV) prevalence on key populations. In this systematic review and meta-analysis, we aimed to provide an overview of HIV prevalence in men who have sex with men (MSM) in Iran. We searched literature published between January 2008 and December 2019 to identify studies reporting the prevalence of HIV infection or acquired immunodeficiency syndrome (AIDS) in a population of adult Iranian men with history of sexual contact with other men. We employed Metaprop command in Stata to pool proportions from different studies. Among the 16 studies retrieved, 2 were performed on MSM population directly, 7 among people who inject drugs, 4 among prisoners, 2 among the homeless, and 1 among methamphetamine users. HIV prevalence was 7% (95% CI, 5%-10%) based on the meta-analysis, although noticeable heterogeneity existed because of target population, study year, and study location, which imposed limitations to provide a robust summary measure for the prevalence of HIV. There is a potential risk of observing a high prevalence of HIV in MSM that could hamper the results of various preventive strategies and their achievements in other subpopulations.
基于信息的决策需求凸显了关键人群中人类免疫缺陷病毒（HIV）流行率数据的重要性。在这项系统评价和荟萃分析中，我们旨在概述伊朗男男性行为者（MSM）中的HIV流行情况。我们检索了2008年1月至2019年12月发表的文献，以确定报告有与其他男性发生性接触史的成年伊朗男性人群中HIV感染或获得性免疫缺陷综合征（AIDS）流行率的研究。我们使用Stata中的Metaprop命令汇总不同研究中的比例。在检索到的16项研究中，2项直接针对男男性行为者人群开展，7项针对注射吸毒者人群，4项针对囚犯人群，2项针对无家可归者人群，1项针对甲基苯丙胺使用者人群。基于荟萃分析，HIV流行率为7%（95%CI，5%-10%），不过由于目标人群、研究年份和研究地点的不同，存在显著的异质性，这给提供一个可靠的HIV流行率汇总指标带来了限制。男男性行为者中存在观察到高HIV流行率的潜在风险，这可能会妨碍各种预防策略的效果及其在其他亚人群中的成果。
