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青少年共发性发育障碍模式:社会经济和遗传因素及其对成年后健康的影响。

Patterns of Co-occurring Developmental Failures in Adolescence: Socioeconomic and Genetic Antecedents and Health Outcomes in Adulthood.

机构信息

Department of Human Development and Family Science, The University of Georgia, Athens, Georgia, United States of America.

Department of Child Psychology and Education/ Social Innovation Convergence Program, Sungkyunkwan University, Seoul, Republic of Korea.

出版信息

Biodemography Soc Biol. 2022 Apr-Jun;67(2):102-121. doi: 10.1080/19485565.2022.2052710. Epub 2022 Mar 23.

DOI:10.1080/19485565.2022.2052710
PMID:35321604
Abstract

This study investigates (1) conjoint latent classes of adolescent co-occurring developmental problems (obesity, depressive symptoms, and low educational attainment), (2) socioeconomic and genetic influences on these classes of adolescents' problem trajectories, and (3) physical health consequences of those latent classes. Data from the National Longitudinal Study of Adolescent to Adult Health (Add Health; = 9,107; mean age = 15.5 years; Female = 52.9 per cent) were used to identify classes of early socioeconomic adversity and conjoint trajectory groups of co-occurring developmental problems. Profiles of social antecedents, genetic endowments (polygenic scores), and physical health outcomes in young adulthood were compared across identified four conjoint trajectory risk groups (overall high-risk, overall low-risk, BMI-risk or obesity, low education-risk). The results showed that youth with overall high-risk and BMI/education-specific risk trajectory groups were more likely to be Black or Hispanic, reported more adverse socioeconomic characteristics and genetic endowment, and averaged significantly poorer physical health in young adulthood compared with youth in the overall low-risk problem trajectory group. Less pronounced differences emerged between the high-risk and problem-specific-risk groups. The findings highlight heterogeneity in adolescent co-occurring developmental problems. Adolescent heterogeneous problem co-development is associated with background socioeconomic and genetic characteristics and physical health in young adulthood.

摘要

本研究调查了(1)青少年共发发育问题(肥胖、抑郁症状和低教育程度)的联合潜在类别,(2)这些青少年问题轨迹的社会经济和遗传影响,以及(3)这些潜在类别的身体健康后果。本研究使用来自青少年至成人健康纵向研究(Add Health;n=9107;平均年龄=15.5 岁;女性=52.9%)的数据,确定了早期社会经济逆境和共发发育问题的联合轨迹群体的类别。在四个共发轨迹风险组(总体高风险、总体低风险、BMI 风险或肥胖、低教育风险)中比较了识别出的社会前因、遗传禀赋(多基因评分)和青年期身体健康结果的特征。结果表明,总体高风险和 BMI/教育特定风险轨迹群体中的年轻人更有可能是黑人或西班牙裔,报告了更多不利的社会经济特征和遗传禀赋,并且与总体低风险问题轨迹群体相比,他们在青年期的身体健康平均明显较差。高风险和特定问题风险组之间的差异不太明显。研究结果突显了青少年共发发育问题的异质性。青少年异质的问题共同发展与青少年期的社会经济和遗传特征以及青年期的身体健康有关。

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