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左腘窝单发Castleman 病 1 例报告

Unicentric castleman disease located in the left popliteal fossa: a case report.

机构信息

Department of Radiology, The Second Affiliated Hospital of Jiaxing University, No.1518, HuanCheng North Road, Jiaxing, Zhejiang Province, China.

出版信息

BMC Musculoskelet Disord. 2022 Mar 23;23(1):278. doi: 10.1186/s12891-022-05213-z.

DOI:10.1186/s12891-022-05213-z
PMID:35321668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8943936/
Abstract

BACKGROUND

Castleman disease (CD) is a lymphoproliferative disease of unknown etiology, it can affect any lymph nodes of the body but rarely affects the popliteal fossa.

CASE PRESENTATION

We present a 67-year-old woman with touching solitary painless mass in the left popliteal fossa for one week. Imaging showed multiple soft-tissue masses of different sizes in the left popliteal muscle space, the T1 weighted image showed hypointense to isointense, the fat-suppressed T2 weighted images showed subtle hypersignal intermingled with linear of hypointense,and displayed homogeneous contrast enhancement after administration of gadolinium. Complete surgical resection was performed. Pathologically demonstrated plasma cell type CD.

CONCLUSION

We described a rare case plasma cell type of UCD located in the popliteal fossa which might help to enrich the clinical spectrum of this rare site and unique subtype of UCD. This case illustrates that CD should be considered in the differential diagnosis of every hypervascularity soft tissue tumor in any anatomic location, especially when they occur in the region of lymph node distribution.

摘要

背景

卡斯特曼病(CD)是一种病因不明的淋巴组织增生性疾病,它可以影响身体的任何淋巴结,但很少影响腘窝。

病例介绍

我们现介绍一位 67 岁女性,1 周前触及左腘窝单发无痛性肿块。影像学显示左腘窝肌间隙内有多个大小不等的软组织肿块,T1 加权图像呈低或等信号,脂肪抑制 T2 加权图像显示混杂的线性低信号和稍高信号,钆剂增强后呈均匀强化。行完全手术切除。病理示浆细胞型 CD。

结论

我们描述了一例罕见的位于腘窝的浆细胞型 UCD,这可能有助于丰富该罕见部位和独特亚型 UCD 的临床谱。该病例提示,CD 应作为任何解剖部位高血管性软组织肿瘤的鉴别诊断,尤其是当它们发生在淋巴结分布区域时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/384f817c9640/12891_2022_5213_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/fa1dd977300e/12891_2022_5213_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/ed7d1f36ec52/12891_2022_5213_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/4a89e9823db4/12891_2022_5213_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/5c8edb54b836/12891_2022_5213_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/53b189b99d94/12891_2022_5213_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/384f817c9640/12891_2022_5213_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/fa1dd977300e/12891_2022_5213_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/ed7d1f36ec52/12891_2022_5213_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/4a89e9823db4/12891_2022_5213_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/5c8edb54b836/12891_2022_5213_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/53b189b99d94/12891_2022_5213_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d48/8943936/384f817c9640/12891_2022_5213_Fig6_HTML.jpg

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特发性Castleman病的治疗
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BMC Cancer. 2011 Aug 12;11:352. doi: 10.1186/1471-2407-11-352.
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