Department for Obstetrics, Medical Faculty, Humboldt University, Campus Rudolf-Virchow, Charité Berlin, Germany.
Department for Obstetrics and Gynaecology, St. Joseph Hospital, Berlin, Germany.
BMC Pregnancy Childbirth. 2022 Mar 23;22(1):241. doi: 10.1186/s12884-022-04519-z.
Sonography based estimate of fetal weight is a considerable issue for delivery planning. The study evaluated the influence of diabetes, obesity, excess weight gain, fetal and neonatal anthropometrics on accuracy of estimated fetal weight with respect to the extent of the percent error of estimated fetal weight to birth weight for different categories.
Multicenter retrospective analysis from 11,049 term deliveries and fetal ultrasound biometry performed within 14 days to delivery. Estimated fetal weight was calculated by Hadlock IV. Percent error from birth weight was determined for categories in 250 g increments between 2500 g and 4500 g. Estimated fetal weight accuracy was categorized as accurate ≤ 10% of birth weight, under- and overestimated by > ± 10% - ± 20% and > 20%.
Diabetes was diagnosed in 12.5%, obesity in 12.6% and weight gain exceeding IOM recommendation in 49.1% of the women. The percentage of accurate estimated fetal weight was not significantly different in the presence of maternal diabetes (70.0% vs. 71.8%, p = 0.17), obesity (69.6% vs. 71.9%, p = 0.08) or excess weight gain (71.2% vs. 72%, p = 0.352) but of preexisting diabetes (61.1% vs. 71.7%; p = 0.007) that was associated with the highest macrosomia rate (26.9%). Mean percent error of estimated fetal weight from birth weight was 2.39% ± 9.13%. The extent of percent error varied with birth weight with the lowest numbers for 3000 g-3249 g and increasing with the extent of birth weight variation: 5% ± 11% overestimation in the lowest and 12% ± 8% underestimation in the highest ranges.
Diabetes, obesity and excess weight gain are not necessarily confounders of estimated fetal weight accuracy. Percent error of estimated fetal weight is closely related to birth weight with clinically relevant over- and underestimation at both extremes. This work provides detailed data regarding the extent of percent error for different birth weight categories and may therefore improve delivery planning.
基于超声的胎儿体重估测对于分娩计划非常重要。本研究评估了糖尿病、肥胖、体重过度增加、胎儿和新生儿人体测量学对不同类别中估计胎儿体重相对于出生体重的%误差程度的影响。
这是一项多中心回顾性分析,纳入了 11049 例足月分娩和胎儿超声生物测量,这些分娩均在分娩前 14 天内完成。通过 Hadlock IV 计算估计胎儿体重。在 2500 g 至 4500 g 之间以 250 g 为增量确定出生体重的类别内的%误差。将估计胎儿体重的准确性分为以下类别:出生体重的准确值为≤10%,低估和高估值为>±10%至±20%和>20%。
在这些女性中,12.5%被诊断为糖尿病,12.6%为肥胖,49.1%体重增加超过 IOM 推荐值。存在母体糖尿病时准确估计胎儿体重的百分比没有显著差异(70.0%比 71.8%,p=0.17)、肥胖(69.6%比 71.9%,p=0.08)或体重过度增加(71.2%比 72%,p=0.352),但对于先前存在的糖尿病(61.1%比 71.7%;p=0.007),其与最高的巨大儿发生率(26.9%)相关。估计胎儿体重与出生体重的平均%误差为 2.39%±9.13%。%误差的程度随出生体重而变化,3000 g-3249 g 时的数值最低,随着出生体重变化的程度增加:最低范围为 5%±11%高估,最高范围为 12%±8%低估。
糖尿病、肥胖和体重过度增加不一定是估计胎儿体重准确性的混杂因素。估计胎儿体重的%误差与出生体重密切相关,在两个极端都有临床相关的高估和低估。本研究提供了不同出生体重类别中%误差程度的详细数据,因此可能会改善分娩计划。