Department of Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.
J Bacteriol. 2022 Apr 19;204(4):e0002722. doi: 10.1128/jb.00027-22. Epub 2022 Mar 24.
Bodhankar et al. reported a noncanonical sensing mechanism that involves signal interaction with the McpA chemoreceptor signaling domain resulting in a chemorepellence response of Bacillus subtilis. The identified repellent binding site is analogous to that for attractant binding in McpB, another B. subtilis chemoreceptor.
Bodhankar 等人报告了一种非经典的感应机制,该机制涉及与 McpA 化学感受受体信号结构域的信号相互作用,导致枯草芽孢杆菌的化学逃避反应。鉴定出的排斥结合位点类似于另一种枯草芽孢杆菌化学感受器 McpB 中吸引剂结合的位点。