Alexandra Gaube, Alexandru Michire, Stefan Calangiu Filip, Petruta-Maria Draghia, Gabriel Burlacu Mihnea, Dragos-Eugen Georgescu, Teodor Georgescu Mihai
National Institute of Infectious Diseases "Prof. Dr. Matei Bals", 021105 Bucharest, Romania.
Department 8 Radiology, Oncology, Hematology, "Carol Davila" University of Medicine and Pharmacy, Bulevardul Eroii Sanitari 8, 050474 Bucharest, Romania.
Hematol Rep. 2022 Mar 2;14(1):24-30. doi: 10.3390/hematolrep14010005.
We conducted an analysis to check whether the ABO blood group impacts the susceptibility or protection against different types of head and neck cancers.
We analyzed the medical records of 61,899 cancer patients from "Prof. Dr. Alexandru Trestioreanu" Institute of Oncology from Bucharest, along with the corresponding blood group type. Data were scraped using Python. For analysis, we used Chi-square test.
The blood group count was A (245, 45.12%) followed by 0 (160, 24.66%), B (110, 20.26%), and AB (28, 5.16%). Hypopharyngeal cancer was associated with B group, oral cavity cancer was associated with a lower risk in patients with B group while AB patients had a higher risk for oral cavity cancer (χ = 36.136, df = 18, = 0.007).
Blood group B is associated with an increased incidence for hypopharyngeal cancer, whereas, for the oral cavity, was associated lower incidence. Blood antigen A is associated with a higher risk of oral cavity cancer development, independent of B blood antigen.
我们进行了一项分析，以检查ABO血型是否会影响对不同类型头颈癌的易感性或保护性。
我们分析了来自布加勒斯特“亚历山德鲁·特雷肖雷亚努教授”肿瘤研究所的61899名癌症患者的病历以及相应的血型类型。数据使用Python进行提取。为了进行分析，我们使用了卡方检验。
血型计数依次为A（245例，45.12%）、O（160例，24.66%）、B（110例，20.26%）和AB（28例，5.16%）。下咽癌与B型血相关，口腔癌在B型血患者中风险较低，而AB型血患者患口腔癌的风险较高（χ = 36.136，自由度 = 18，P = 0.007）。
B型血与下咽癌发病率增加相关，而对于口腔癌，B型血与较低发病率相关。血型抗原A与口腔癌发生风险较高相关，独立于B血型抗原。
