Laboratory of Plant Biotechnology, Ecology and Ecosystem Valorization-URL CNRST N°10, Faculty of Sciences El Jadida, University Chouaib Doukkali, P.O. Box 20, El Jadida 24000, Morocco.
Department of Biology, Faculty of Sciences El Jadida, University Chouaib Doukkali, P.O. Box 20, El Jadida 24000, Morocco.
Mar Drugs. 2022 Feb 25;20(3):169. doi: 10.3390/md20030169.
Volatile compounds from the marine cyanolichen , collected from the Moroccan Atlantic coast, were extracted by hydrodistillation and their putative chemical composition was investigated by gas chromatography coupled to mass spectrometry (GC/MS). Based on the obtained results, volatile compounds (LPVCs) were mainly dominated by sesquiterpenes compounds, where -himachalene, -himachalene, ()-2,4 decadienal and -himachalene were assumed to be the most abundant constituents, with percentage of 37.51%, 11.71%, 8.59% and 7.62%, respectively. LPVCs depicted significant antimicrobial activity against all tested strains ( CCMM B3, DSM 50090, ATCC 8739 and CCMM-L4) with minimum inhibitory concentration (MIC) values within the range of 1.69-13.5 mg/mL. Moreover, this LPVC showed interesting scavenging effects on the 2,2-diphenyl-1-picrylhydrazyl radical with an IC of 0.21 mg/mL. LPVCs could be an approving resource with moderate antimicrobial potential and interesting antioxidant activity for cosmetics and pharmaceutical applications.
从摩洛哥大西洋沿岸采集的海洋蓝藻中的挥发性化合物通过水蒸馏提取，并通过气相色谱-质谱联用（GC/MS）研究其可能的化学成分。基于获得的结果，挥发性化合物（LPVCs）主要由倍半萜化合物组成，其中 -himachalene、-himachalene、()-2,4 癸二烯醛和 -himachalene 被认为是最丰富的成分，分别占 37.51%、11.71%、8.59%和 7.62%。LPVCs 对所有测试菌株（CCMM B3、DSM 50090、ATCC 8739 和 CCMM-L4）表现出显著的抗菌活性，最小抑菌浓度（MIC）值在 1.69-13.5mg/mL 范围内。此外，这种 LPVC 对 2,2-二苯基-1-苦基肼自由基具有有趣的清除作用，IC 为 0.21mg/mL。LPVCs 可能是一种有前途的资源，具有适度的抗菌潜力和有趣的抗氧化活性，可用于化妆品和制药应用。
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