温胆汤：一种治疗头痛疾病的潜在经方？
Wen Dan Tang: A Potential Jing Fang Decoction for Headache Disorders?
作者信息
Pradhan Saroj K, Li Yiming, Gantenbein Andreas R, Angst Felix, Lehmann Susanne, Shaban Hamdy
机构信息
Research Department Rehaklinik, TCM Ming Dao, ZURZACH Care, 5330 Bad Zurzach, Switzerland.
Research Department, Swiss TCM Academy, 5330 Bad Zurzach, Switzerland.
出版信息
Medicines (Basel). 2022 Mar 4;9(3):22. doi: 10.3390/medicines9030022.
BACKGROUND
Chinese herbal medicine is considered relatively safe, inexpensive, and easily accessible. Wen Dan Tang (WDT), a Jing Fang ancient classical Chinese herbal formula with a broad indication profile has been used for several centuries in China to treat various illnesses.
QUESTION
Are there evidence-based clinical trials that show that WDT has a significant impact on the treatment of various diseases, especially in patients with migraine and tension-type headaches (TTH)?
METHODS
This study is based on an online database search using PubMed, Medline, Cochrane Library, AcuTrials, Embase, Semantic Scholar, Jstor, internet research, and review of ancient and modern Chinese medical textbooks regarding WDT and its compounds.
RESULTS
There were no studies on WDT in migraine and TTH; therefore, this work gathers and describes data for every single compound in the formula.
CONCLUSION
This study suggests that the bioactive compounds found in WDT composition show potential in treating patients with neurological, psychiatric disorders, cardiovascular diseases, metabolic syndrome, and digestive disorders. Some coherence between WDT in headache reduction and improvements in the quality of life in patients with migraines and TTH could be evaluated, showing positive results of WDT in these patients.
背景
中药被认为相对安全、廉价且易于获取。温胆汤（WDT）是一种经方古代经典中药配方，适应证广泛，在中国已使用了几个世纪来治疗各种疾病。
问题
是否有基于证据的临床试验表明温胆汤对各种疾病的治疗有显著影响，特别是对偏头痛和紧张型头痛（TTH）患者？
方法
本研究基于在线数据库搜索，使用了PubMed、Medline、Cochrane图书馆、AcuTrials、Embase、语义学者、Jstor、互联网研究，并查阅了关于温胆汤及其成分的古今中医教科书。
结果
没有关于温胆汤治疗偏头痛和紧张型头痛的研究；因此，本研究收集并描述了该方剂中每种成分的数据。
结论
本研究表明，温胆汤成分中发现的生物活性化合物在治疗神经、精神疾病、心血管疾病、代谢综合征和消化系统疾病患者方面具有潜力。可以评估温胆汤在减轻偏头痛和紧张型头痛患者头痛以及改善其生活质量方面的一些相关性，显示温胆汤对这些患者有积极效果。
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