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[儿童肝硬化——病因、诊断与保守治疗]

[Liver cirrhosis in childhood--etiology, diagnosis and conservative therapy].

作者信息

Feist D

出版信息

Wien Klin Wochenschr. 1986 Aug 29;98(16):547-51.

PMID:3532572
Abstract

Liver cirrhosis is relatively rare in children as compared to adults; frequently it is diagnosed too late. Biliary cirrhosis of early childhood is often the result of neonatal cholestatic syndromes. Beyond infancy, cirrhosis as a consequence of chronic active autoimmune hepatitis or of Wilson's disease may be prevented, if causal therapy is begun in time. Hence paediatricians should exclude both diseases in all children with elevated transaminases and clinical features of a liver disorder.

摘要

与成人相比,肝硬化在儿童中相对少见;通常确诊时已为时过晚。儿童早期的胆汁性肝硬化常由新生儿胆汁淤积综合征引起。婴儿期过后,如果能及时开始病因治疗,慢性活动性自身免疫性肝炎或威尔逊病所致的肝硬化是可以预防的。因此,儿科医生应在所有转氨酶升高且有肝病临床特征的儿童中排除这两种疾病。

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