Siwinska Natalia, Janus Izabela, Zak-Bochenek Agnieszka, Noszczyk-Nowak Agnieszka
Department of Internal Medicine and Clinic of Diseases of Horses, Dogs and Cats, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Division of Pathomorphology and Veterinary Forensics, Department of Pathology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Animals (Basel). 2022 Mar 15;12(6):732. doi: 10.3390/ani12060732.
It has been well established that obesity in horses can have a negative impact on their health, including endocrine disturbances. In humans, it is well known that obesity leads to structural and functional changes of the cardiovascular system. The aim of the study was to assess the impact of obesity on the histological structure of the myocardial tissue, as well as great and peripheral arteries in horses. The heart, arteries (aorta, pulmonary artery and palmar arteries) specimens from 7 horses with normal BCS (4-5/9) and 12 extremely obese (BCS 9/9) draft slaughter horses were obtained for histopathological evaluation. The heart tissue and great arteries showed more intense disturbances in the architecture and vacuolization in the aorta in obese horses as compared to the healthy group. The intima in the pulmonary artery, coronary arteries and palmar arteries was thicker in the obese, rather than healthy horses. The palmar arteries in obese horses had a larger lumen diameter and the lumen-to-total diameter ratio as compared to the control group. The presented study showed a significant effect of obesity on the heart as well as the central and peripheral vessels in horses. This forms the basis for a deeper reflection on the impact of obesity on the equine body.
马的肥胖会对其健康产生负面影响，包括内分泌紊乱，这一点已经得到充分证实。在人类中，众所周知肥胖会导致心血管系统的结构和功能变化。本研究的目的是评估肥胖对马的心肌组织以及大动脉和外周动脉组织学结构的影响。从7匹体况评分正常（4 - 5/9）的马和12匹极度肥胖（体况评分9/9）的役用屠宰马获取心脏、动脉（主动脉、肺动脉和掌动脉）标本进行组织病理学评估。与健康组相比，肥胖马的心脏组织和大动脉显示出更严重的结构紊乱以及主动脉空泡化。肥胖马的肺动脉、冠状动脉和掌动脉内膜比健康马更厚。与对照组相比，肥胖马的掌动脉管腔直径和管腔与总直径之比更大。本研究表明肥胖对马的心脏以及中央和外周血管有显著影响。这为更深入思考肥胖对马身体的影响奠定了基础。
