Villa Luca, Gazzonis Alessia Libera, Fumagalli Emanuele, Zanzani Sergio Aurelio, Manfredi Maria Teresa
Department of Veterinary Medicine and Animal Sciences, Università degli Studi di Milano, Via dell'Università 6, 26900 Lodi, Italy.
Independent Researcher, 24121 Bergamo, Italy.
Animals (Basel). 2022 Mar 20;12(6):786. doi: 10.3390/ani12060786.
is recognized as a major cause of abortion in cattle, determining economic losses, particularly in dairy industries. To evaluate the impact of neosporosis on herd efficiency, and to understand how the serological analysis for is explicative of the farm picture, an epidemiological study was designed in two dairy farms recruited as a case study. Blood samples were collected from 540 animals, including cows and heifers over 12 months, and analyzed by an indirect immunofluorescent antibody test with subsequent antibody titration. Overall, 94 animals (17.4%) were identified as positive to antibodies (15.5% and 18.5% in Farm 1 and Farm 2), with differences between the farms concerning the antibody titers (Chi-square, -value = 0.04), particularly in cows (Chi-square, -value = 0.018). Consequently, a different pattern of abortion episodes was depicted in the two investigated farms. Considering reproductive and productive performances, the number of inseminations necessary to make an animal pregnant was higher in seropositive cows (2.4 and 2.9 in Farm 1 and 2, respectively) than in seronegative ones (2.1 and 2.4 in Farm 1 and 2, respectively). Similarly, particularly in Farm 1, the number of days in milk of not-pregnant cows was higher in seropositive (167.7) than seronegative animals (133.4). Moreover, although the association between infection and milk production is still unclear, both the daily milk production and the 305-mature equivalent milk yield were lower in seropositive (31.02 and 11,838.94) than seronegative cows (33.59 and 12,274.88) in Farm 1; an opposite pattern was otherwise depicted in Farm 2. The study showed that even if circulated equally in the two herds, the dynamics of the parasite infection and its outcome may be different, also depending on the specific situation of the farm. In this way, the integration of serological analysis for , the reproductive and productive parameters, and the information on herd performances, could give specific indications for the application of control strategies.
被认为是牛流产的主要原因，会造成经济损失，尤其是在奶牛业。为了评估新孢子虫病对牛群生产效率的影响，并了解针对[具体病原体名称缺失]的血清学分析如何解释农场的情况，在两个被招募作为案例研究的奶牛场设计了一项流行病学研究。从540头动物身上采集血样，包括12个月以上的奶牛和小母牛，并通过间接免疫荧光抗体试验及后续抗体滴定进行分析。总体而言，94头动物（17.4%）被鉴定为[具体病原体名称缺失]抗体阳性（农场1和农场2分别为15.5%和18.5%），两个农场在抗体滴度方面存在差异（卡方检验，P值 = 0.04），在奶牛中差异尤为明显（卡方检验，P值 = 0.018）。因此，在两个被调查的农场中描绘出了不同的流产情况模式。考虑到繁殖和生产性能，血清阳性奶牛使动物怀孕所需的授精次数（农场1和2分别为2.4次和2.9次）高于血清阴性奶牛（农场1和2分别为2.1次和2.4次）。同样，特别是在农场1，未怀孕奶牛的泌乳天数在血清阳性组（167.7天）高于血清阴性组（133.4天）。此外，尽管[具体病原体名称缺失]感染与产奶量之间的关联仍不明确，但在农场1中，血清阳性奶牛（分别为31.02和11,838.94）的日产奶量和305天成熟当量产奶量均低于血清阴性奶牛（分别为33.59和12,274.88）；而在农场2中则呈现相反的模式。该研究表明，即使[具体病原体名称缺失]在两个牛群中传播程度相同，寄生虫感染的动态及其结果可能也会不同，这也取决于农场的具体情况。通过这种方式，将针对[具体病原体名称缺失]的血清学分析、繁殖和生产参数以及牛群生产性能信息相结合，可以为控制策略的应用提供具体指导。
