新冠病毒感染患者红细胞的形态功能特征研究
Research into Morphofunctional Characteristics of Erythrocytes in COVID-19 Patients.
作者信息
Revin Victor, Balykova Larisa, Pinyaev Sergey, Syusin Ilya, Radaeva Olga, Revina Nadezhda, Kostina Yuliya, Kozlov Evgeniy, Inchina Vera, Nikitin Igor, Salikov Alexandr, Fedorov Ilya
机构信息
Federal State Budgetary Educational Institution of Higher Education, Ogarev Mordovia State University, 430005 Saransk, Russia.
Federal State Autonomous Institution, Treatment and Rehabilitation Center of the Ministry of Health of the Russian Federation, 125367 Moscow, Russia.
出版信息
Biomedicines. 2022 Feb 25;10(3):553. doi: 10.3390/biomedicines10030553.
In this paper, the erythrocytes of healthy donors and people with a confirmed diagnosis of COVID-19 were tested by Raman spectroscopy and laser interference microscopy. We argue that erythrocytes (red blood cells) in COVID-19 patients have an irregular shape, and their morphometric characteristics are impaired in comparison to healthy red blood cells. Raman spectroscopy also allows us to detect a decreased oxygen transport function of these erythrocytes. The combination of these methods-Raman spectroscopy and laser interference microscopy-is a highly effective method for the diagnosis of SARS-CoV-2.
在本文中，通过拉曼光谱和激光干涉显微镜对健康献血者和确诊为新冠肺炎的患者的红细胞进行了检测。我们认为，新冠肺炎患者的红细胞形状不规则，与健康红细胞相比，其形态测量特征受损。拉曼光谱还使我们能够检测到这些红细胞的氧运输功能下降。拉曼光谱和激光干涉显微镜这两种方法的结合是诊断新型冠状病毒的一种高效方法。
Zotero 插件