Úbeda-D'Ocasar Edurne, Valera-Calero Juan Antonio, Gallego-Sendarrubias Gracia María, Fernández-de-Las-Peñas César, Arias-Buría José Luis, Morales-Cabezas Matilde, Arendt-Nielsen Lars, Cigarán-Méndez Margarita
Department of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, 28692 Villanueva de la Cañada, Spain.
VALTRADOFI Research Group, Department of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, 28692 Villanueva de la Cañada, Spain.
Biomedicines. 2022 Mar 6;10(3):612. doi: 10.3390/biomedicines10030612.
We aimed to analyze potential correlations between S-LANSS and PainDETECT with proxies for pain sensitization, e.g., the Central Sensitization Inventory (CSI) and pressure pain hyperalgesia (construct validity), pain-related or psychological variables (concurrent validity) in women with fibromyalgia (FMS). One-hundred-and-twenty-six females with FMS completed demographic, pain-related variables, psychological, and sensitization outcomes as well as the S-LANSS and the PainDETECT questionnaires. S-LANSS was positively associated with BMI (r = 0.206), pain intensity (r = 0.206 to 0.298) and CSI score (r = 0.336) and negatively associated with all PPTs (r = -0.180 to -0.336). PainDETECT was negatively associated with age (r = -0.272) and all PPTs (r = -0.226 to -0.378) and positively correlated with pain intensity (r = 0.258 to 0.439), CSI (r = 0.538), anxiety (r = 0.246) and depression (r = 0.258). 51.4% of the S-LANSS was explained by PainDETECT (45.3%), posterior iliac PPT (0.2%) and mastoid PPT (5.9%), whereas the 56.4% of PainDETECT was explained by S-LANSS (43.4%), CSI (10.4%), and pain intensity (2.6%). This study found good convergent association between S-LANSS and PainDETECT in women with FMS. Additionally, S-LANSS was associated with PPTs whereas PainDETECT was associated with pain intensity and CSI, suggesting that both questionnaires assess different spectrums of the neuropathic and pain sensitization components of a condition and hence provide synergistic information.
我们旨在分析在纤维肌痛（FMS）女性患者中，S-LANSS和疼痛检测量表（PainDETECT）与疼痛敏化指标之间的潜在相关性，这些指标如中枢敏化量表（CSI）和压力疼痛超敏反应（结构效度）、疼痛相关或心理变量（同时效度）。126名患有FMS的女性完成了人口统计学、疼痛相关变量、心理和敏化结果以及S-LANSS和疼痛检测量表问卷。S-LANSS与体重指数（BMI）呈正相关（r = 0.206）、与疼痛强度呈正相关（r = 0.206至0.298）以及与CSI评分呈正相关（r = 0.336），而与所有压痛阈（PPT）呈负相关（r = -0.180至-0.336）。疼痛检测量表与年龄呈负相关（r = -0.272）以及与所有压痛阈呈负相关（r = -0.226至-0.378），并与疼痛强度呈正相关（r = 0.258至0.439）、与CSI呈正相关（r = 0.538）、与焦虑呈正相关（r = 0.246）以及与抑郁呈正相关（r = 0.258）。51.4%的S-LANSS可由疼痛检测量表（45.3%）、髂后压痛阈（0.2%）和乳突压痛阈（5.9%）解释，而56.4%的疼痛检测量表可由S-LANSS（43.4%）、CSI（10.4%）和疼痛强度（2.6%）解释。本研究发现，在患有FMS的女性中，S-LANSS和疼痛检测量表之间存在良好的趋同关联。此外，S-LANSS与压痛阈相关，而疼痛检测量表与疼痛强度和CSI相关，这表明这两种问卷评估了一种病症的神经病理性和疼痛敏化成分的不同方面，因此提供了协同信息。
