Abreo K, Abreo F, Mitchell B, Schloemer G
Am J Kidney Dis. 1986 Oct;8(4):257-61. doi: 10.1016/s0272-6386(86)80036-1.
A case of idiopathic crescentic membranous glomerulonephritis is reported. In addition to the present case, eight cases of this type of glomerulonephritis reported in the literature are reviewed. This is an uncommon form of glomerulonephritis, seen in middle age and in both sexes. Clinical presentation is similar to idiopathic membranous nephropathy. Lupus and antiglomerular-basement membrane nephritis should be excluded by serological tests. Prognosis is grave, resulting in end-stage renal failure (ESRD) within a year in most patients. There is no specific therapy known to alter the course of the disease. In this patient, short courses of high-dose corticosteroids, administered during flares of glomerulonephritis, seemed to improve renal function.
报告了一例特发性新月体性膜性肾小球肾炎病例。除本病例外，还对文献中报道的8例此类肾小球肾炎进行了综述。这是一种不常见的肾小球肾炎形式，见于中年人群，男女均可发病。临床表现与特发性膜性肾病相似。应通过血清学检查排除狼疮和抗肾小球基底膜肾炎。预后严重，大多数患者在一年内会发展为终末期肾衰竭（ESRD）。目前尚无已知的特异性疗法可改变疾病进程。在该患者中，在肾小球肾炎发作期间给予短疗程大剂量糖皮质激素似乎改善了肾功能。
