Mitas J A, Frank L R, Swerdlin A R, Johnson D L, Rabetoy G M
South Med J. 1983 May;76(5):664-7. doi: 10.1097/00007611-198305000-00036.
We describe the course of a patient with multiple rectal abscesses and progressive renal dysfunction. A renal biopsy demonstrated a membranous glomerulopathy associated with extensive crescent formation. No underlying cause for the glomerulonephritis could be identified and, specifically, the anti-GBM antibody present in other similar cases was not found. There appears to be a subset of patients with membranous glomerulopathy in whom crescents develop with rapid loss of renal function. Anti-GBM antibody is not necessary in the pathogenesis of this lesion.
我们描述了一名患有多发性直肠脓肿和进行性肾功能不全患者的病程。肾脏活检显示为膜性肾小球病，伴有广泛的新月体形成。未发现肾小球肾炎的潜在病因，具体而言，未检测到其他类似病例中存在的抗肾小球基底膜（GBM）抗体。似乎有一部分膜性肾小球病患者会出现新月体，并伴有肾功能迅速丧失。在这种病变的发病机制中，抗GBM抗体并非必需。
