Jin Chao, Liu Zhiyuan, Yu Wei, Qin Chunling, Yu Hui, Wang Zhifeng
Key Laboratory for New Type of Functional Materials in Hebei Province, School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300401, China.
Research Institute of Foundry, Hebei University of Technology, Tianjin 300401, China.
Materials (Basel). 2022 Mar 15;15(6):2172. doi: 10.3390/ma15062172.
Biodegradable Mg-Zn-Ca-based metallic glasses (MGs) present improved strength and superior corrosion resistance, compared to crystalline Mg. In particular, in vivo and in vitro attempts reveal that biodegradable Mg-Zn-Ca-based MGs possess excellent biocompatibility, suggesting that they are ideal candidates for temporary implant materials. However, the limited size and severe brittleness prevent their widespread commercialization. In this review, we firstly summarize the microstructure characteristic and mechanical properties of Mg-Zn-Ca-based MGs. Then, we provide a comprehensive and systematic understanding of the recent progress of the biocorrosion and biocompatibility of Mg-Zn-Ca-based MGs. Last, but not least, the outlook towards the fabrication routes, composition design, structure design, and reinforcement approaches of Mg-Zn-Ca-based MGs are briefly proposed.
与结晶态镁相比，可生物降解的镁锌钙基金属玻璃（MGs）具有更高的强度和卓越的耐腐蚀性。特别是，体内和体外实验表明，可生物降解的镁锌钙基金属玻璃具有出色的生物相容性，这表明它们是临时植入材料的理想候选者。然而，尺寸受限和严重的脆性阻碍了它们的广泛商业化。在这篇综述中，我们首先总结了镁锌钙基金属玻璃的微观结构特征和力学性能。然后，我们对镁锌钙基金属玻璃的生物腐蚀和生物相容性的最新进展进行了全面系统的了解。最后但同样重要的是，简要提出了镁锌钙基金属玻璃的制造路线、成分设计、结构设计和增强方法的展望。
