Sánchez-González Juan Luis, Sánchez-Rodríguez Juan Luis, Juárez-Vela Raúl, Ruiz de Viñaspre-Hernandez Regina, González-Sarmiento Rogelio, Martin-Vallejo Francisco Javier
Department of Nursery and Physiotherapy, Faculty of Nursery and Physiotherapy, University of Salamanca, 37007 Salamanca, Spain.
Department of Basic Psychology, Psychobiology and Methodology, Faculty of Psychology, University of Salamanca, 37005 Salamanca, Spain.
J Clin Med. 2022 Mar 21;11(6):1728. doi: 10.3390/jcm11061728.
During the normal aging process, a series of events occur, such as a decrease in telomere length and a decrease in various cognitive functions, such as attention, memory, or perceptual-motor speed. Several studies have attempted to establish a correlation between both variables; however, there is considerable controversy in the scientific literature. The aim of our study was to establish a correlation between the scores obtained in the following different cognitive tests: the Mini-Mental State Examination, the Benton Visual Retention Test, the Trail Making Test, the Rey Auditory Verbal Learning Test, the Stroop Test, and the measurement of telomere length. The sample consisted of a total of 41 physically active, healthy women, with a mean age of 71.21 (±4.32) and of 33 physically inactive, healthy women, with a mean age of 72.70 (±4.13). Our results indicate that there is no correlation between the scores obtained by the women in either group and their telomere length. Therefore, it is not possible to conclude that telomere length can be correlated with cognitive performance.
在正常衰老过程中，会发生一系列事件，比如端粒长度缩短以及多种认知功能下降，如注意力、记忆力或感知运动速度下降。多项研究试图在这两个变量之间建立关联；然而，科学文献中存在相当大的争议。我们研究的目的是在以下不同认知测试中获得的分数与端粒长度测量值之间建立关联：简易精神状态检查表、本顿视觉保持测验、连线测验、雷伊听觉词语学习测验、斯特鲁普测验。样本总共包括41名身体活跃的健康女性，平均年龄为71.21（±4.32）岁，以及33名身体不活跃的健康女性，平均年龄为72.70（±4.13）岁。我们的结果表明，两组女性获得的分数与她们的端粒长度之间均无关联。因此，无法得出端粒长度与认知表现相关的结论。
